| Weight | 215.035 g/mol |
|---|---|
| Formula | C9H4Cl2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
3,4-dichloroisocoumarin (51050-59-0)
3,4-DCL
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- Sigma-Aldrich - 3,4-dichloroisocoumarin163.50 - 659.00 USD
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- Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor. (Biochemistry, 1985)
- A 3,4-dichloroisocoumarin-resistant component of the multicatalytic proteinase complex. (Biochemistry, 1992)
- Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate. (Journal of Biological Chemistry, 2012)
- Reactions of [14C]-3,4-dichloroisocoumarin with subunits of pituitary and spleen multicatalytic proteinase complexes (proteasomes). (Biochemistry, 1997)
- Interleukin 1-induced phosphorylation of MAD3, the major inhibitor of nuclear factor kappa B of HeLa cells. Interference in signalling by the proteinase inhibitors 3,4-dichloroisocoumarin and tosylphenylalanyl chloromethylketone. (Biochemical Journal, 1995)
- 3,4-dichloroisocoumarin-induced activation of the degradation of beta-casein by the bovine pituitary multicatalytic proteinase complex. (Journal of Biological Chemistry, 1992)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 3,4-DCL
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SMILESC1=CC=C2C(=C1)C(=C(OC2=O)Cl)Cl
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InChIKeySUGXUUGGLDCZKB-UHFFFAOYSA-N
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3,4-dichloroisocoumarin
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