Weight | 226.188 g/mol |
---|---|
Formula | C9H10N2O5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 4 |
3-Nitro-L-tyrosine (3604-79-3, 621-44-3)
nitrotyrosine · 3-nitrotyrosine · 3-mononitrotyrosine
Score:
#840 in Neuroscience
,
#1623 in Biochemistry
,
#3689 in Biology
,
#4637 in Chemistry
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- Sigma-Aldrich - 3-Nitro-L-tyrosine88.30 - 352.00 USD
- Fisher Scientific - Search for 3-Nitro-L-tyrosine
- TCI - 3-Nitro-L-tyrosine84.00 - 292.00 USD
- EVIDENCE FOR NITRIC OXIDE-MEDIATED OXIDATIVE DAMAGE IN CHRONIC INFLAMMATION : NITROTYROSINE IN SERUM AND SYNOVIAL FLUID FROM RHEUMATOID PATIENTS (FEBS Letters, 1994)
- Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. (Journal of Clinical Investigation, 1994)
- Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease (Gastroenterology, 1996)
- Increased 3nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis (Annals of Neurology, 1997)
- Inducible Nitric Oxide Synthase, Nitrotyrosine, and Apoptosis in Helicobacter pylori Gastritis: Effect of Antibiotics and Antioxidants (Cancer Research, 1996)
- A tale of two controversies. Defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species (Journal of Biological Chemistry, 2002)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - nitrotyrosine
- 3-nitrotyrosine
- 3-mononitrotyrosine
- 3-nitrotyrosine, (DL)-isomer
- 3-nitrotyrosine, (L)-isomer
-
SMILESC1=CC(=C(C=C1CC(C(=O)O)N)[N+](=O)[O-])O
-
InChIKeyFBTSQILOGYXGMD-UHFFFAOYSA-N
- Pubchem - 3-Nitro-L-tyrosine
- Wikipedia - 3-nitrotyrosine
Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen dioxide. Nitrotyrosine is identified as an indicator or marker of cell damage, inflammation as well as NO (nitric oxide) production. Nitrotyrosine is formed in the presence of the active metabolite NO.
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