Weight | 293.087 g/mol |
---|---|
Formula | C7H15Cl2N2O4P |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 0 |
Rotatable Bonds | 6 |
4-Hydroperoxycyclophosphamide (39800-16-3)
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- Autologous Bone Marrow Transplantation in Patients with Acute Nonlymphocytic Leukemia, Using ex Vivo Marrow Treatment with 4-Hydroperoxycyclophosphamide (The New England Journal of Medicine, 1986)
- Pharmacokinetics of Interstitial Delivery of Carmustine, 4-Hydroperoxycyclophosphamide, and Paclitaxel from a Biodegradable Polymer Implant in the Monkey Brain (Cancer Research, 1998)
- Elimination of acute myelogenous leukemic cells from marrow and tumor suspensions in the rat with 4-hydroperoxycyclophosphamide (Blood, 1980)
- DNA Repair Initiated in Chronic Lymphocytic Leukemia Lymphocytes by 4-Hydroperoxycyclophosphamide Is Inhibited by Fludarabine and Clofarabine (Clinical Cancer Research, 2001)
- Autologous bone marrow transplantation in acute leukemia: A phase I study of in vitro treatment of marrow with 4-hydroperoxycyclophosphamide to purge tumor cells (Blood, 1985)
- CFU-GM content of bone marrow graft correlates with time to hematologic reconstitution following autologous bone marrow transplantation with 4- hydroperoxycyclophosphamide-purged bone marrow (Blood, 1987)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1COP(=O)(NC1OO)N(CCCl)CCCl
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- Pubchem - 4-Hydroperoxycyclophosphamide
- Wikipedia - 4-hydroperoxycyclophosphamide
Perfosfamide, or 4-hydroperoxycyclophosphamide (trade name Pergamid) was an experimental drug candidate for blood cancers that was rejected by the FDA in 1993 and never reached the market.
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