Weight | 318.501 g/mol |
---|---|
Formula | C21H34O2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 1 |
5|A-Pregnan-3|A-Ol-20-One (128-20-1)
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SMILESCC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
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InChIKeyAURFZBICLPNKBZ-UHFFFAOYSA-N
- Pubchem - 5|A-Pregnan-3|A-Ol-20-One
- Wikipedia - eltanolone
Pregnanolone, also known as eltanolone (INN), as well as 3,5-tetrahydroprogesterone (3,5-THP) or 3-hydroxy-5-pregnan-20-one, is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects. It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for this reason was never marketed.
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