| Weight | 325.408 g/mol |
|---|---|
| Formula | C20H23NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
56195-50-7 (56195-50-7)
nalodeine · N-allylnorcodeine · nalodeine hydrobromide, (5alpha,6alpha)-isomer
Suppliers
- Sigma-Aldrich - Search for 56195-50-7
- Fisher Scientific - Search for 56195-50-7
- TCI - Search for 56195-50-7
Alternate Names
- nalodeine
- N-allylnorcodeine
- nalodeine hydrobromide, (5alpha,6alpha)-isomer
-
SMILESCOC1=C2C3=C(CC4C5C3(CCN4CC=C)C(O2)C(C=C5)O)C=C1
-
InChIKeyXAOWELGMJQTJQR-UHFFFAOYSA-N
External Links
- Pubchem - 56195-50-7
- Wikipedia - Nalodeine
Nalodeine, also known more commonly as N-allylnorcodeine, is an opioid antagonist (specifically, an antagonist of the -opioid receptor) that was never marketed but is of notability in having been the first opioid antagonist to have been discovered. It was first reported in 1915, and this was followed by the clinical introduction of nalorphine (N-allylnormorphine) in 1954, naloxone (N-allyloxymorphone) in 1960, and naltrexone (N-methylcyclopropyloxymorphone) in 1963. Nalmefene (6-desoxy-6-methylene-naltrexone), another structurally related opioid antagonist derivative, was also subsequently introduced, in 1996.
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