| Weight | 167.197 g/mol |
|---|---|
| Formula | C5H5N5S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
6-Thioguanine (154-42-7, 5580-03-0)
Tabloid · Thioguanine · Lanvis
Score:
#475 in Biochemistry
,
#1518 in Biology
,
#1780 in Chemistry
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- Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. (Journal of Biological Chemistry, 2001)
- T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood. (Proceedings of the National Academy of Sciences of the United States of America, 1982)
- Double Induction Strategy for Acute Myeloid Leukemia: The Effect of High-Dose Cytarabine With Mitoxantrone Instead of Standard-Dose Cytarabine With Daunorubicin and 6-Thioguanine: A Randomized Trial by the German AML Cooperative Group (Blood, 1999)
- Thiopurine pharmacogenetics in leukemia: Correlation of erythrocyte thiopurine methyltransferase activity and 6thioguanine nucleotide concentrations (Clinical Pharmacology & Therapeutics, 1987)
- Role of Postreplicative DNA Mismatch Repair in the Cytotoxic Action of Thioguanine (Science, 1996)
- Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. (Gastroenterology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tabloid
- Thioguanine
- Lanvis
- 6 Thioguanine
- Thioguanine Monosodium Salt
- Thioguanine Anhydrous
- Thioguanin GSK
- GlaxoSmithKline Brand of Tioguanine
- Glaxo Wellcome Brand of Tioguanine
- ThioguaninGSK
- Thioguanin-GSK
- Wellcome Brand of Thioguanine
- Thioguanine Hemihydrate
- Thioguanine Tabloid
- Tioguanina Wellcome
- GlaxoSmithKline Brand of Thioguanine
- Glaxo Wellcome Brand of Thioguanine
- 2 Amino 6 Purinethiol
- Tioguanine
- 2-amino-6-purinethiol
- Tioguanine GlaxoSmithKline Brand
-
SMILESC1=NC2=C(N1)C(=S)N=C(N2)N
-
InChIKeyWYWHKKSPHMUBEB-UHFFFAOYSA-N
- Pubchem - 6-Thioguanine
- Wikipedia - thioguanine
Tioguanine, also known as thioguanine or 6-thioguanine (6-TG) is a medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myeloid leukemia (CML). Long term use is not recommended. It is given by mouth.
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