Weight | 324.402 g/mol |
---|---|
Formula | C15H20N2O4S |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 4 |
acetohexamide (968-81-0)
Dymelor · Dimelor · Gamadiabet
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- Sigma-Aldrich - acetohexamide44.90 - 338.10 USD
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- THE NATURE OF THE METABOLITES OF ACETOHEXAMIDE IN THE RAT AND IN THE HUMAN (Journal of Pharmacology and Experimental Therapeutics, 1965)
- Potentiation of Acetohexamide Hypoglycemia by Phenylbutazone (The New England Journal of Medicine, 1967)
- The effects of long-term acetohexamide treatment on pancreatic islet cell function in maturity-onset diabetes (Metabolism-clinical and Experimental, 1966)
- CHROMATOGRAPHIC ANALYSIS OF ACETOHEXAMIDE BINDING TO GLYCATED HUMAN SERUM ALBUMIN (Journal of Chromatography B, 2010)
- Extended Hildebrand Solubility Approach: Solubility of Tolbutamide, Acetohexamide, and Sulfisomidine in Binary Solvent Mixtures (Journal of Pharmaceutical Sciences, 1982)
- Metabolism, Blood Levels and Rate of Excretion of Acetohexamide in Human Subjects (Diabetes, 1967)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dymelor
- Dimelor
- Gamadiabet
-
SMILESCC(=O)C1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2
-
InChIKeyVGZSUPCWNCWDAN-UHFFFAOYSA-N
- Pubchem - acetohexamide
- Wikipedia - acetohexamide
Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.
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Synthesis
Reactant
+
4-Acetylbenzenesulfonamide
(Schotten-Baumann amide from acid)
Reactant
+
CHLOROCYCLOHEXANE
(Alkylation of primary amines)
Reactant
+
CYCLOHEXYLAMINE
(Thiourea)
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