| Weight | 154.125 g/mol |
|---|---|
| Formula | C6H6N2O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
ACIPIMOX (51037-30-0)
Olbemox · 5-methylpyrazine-2-carboxylic acid 4-oxide · Olbetam
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- TCI - ACIPIMOX66.00 - 199.00 USD
- Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. (Diabetes, 1999)
- Effects of insulin and acipimox on VLDL1 and VLDL2 apolipoprotein B production in normal subjects. (Diabetes, 1998)
- Inhibition of lipolysis by nicotinic acid and by acipimox. (Clinical Pharmacology & Therapeutics, 1980)
- Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus. (Journal of Clinical Investigation, 1991)
- Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression. (The Journal of Clinical Endocrinology and Metabolism, 1996)
- The effect of nicotinic acid and acipimox on lipoprotein(a) concentration and turnover. (Atherosclerosis, 1993)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Olbemox
- 5-methylpyrazine-2-carboxylic acid 4-oxide
- Olbetam
- 5-methylpyrazinecarboxylic acid 4-oxide
- Nedios
-
SMILESCC1=CN=C(C=[N+]1[O-])C(=O)O
-
InChIKeyDJQOOSBJCLSSEY-UHFFFAOYSA-N
- Pubchem - ACIPIMOX
- Wikipedia - acipimox
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent. It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.
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