Weight | 477.563 g/mol |
---|---|
Formula | C26H29F2N7 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 2 |
Aromatic Rings | 3 |
Rotatable Bonds | 10 |
ALMITRINE (27469-53-0)
Almitrine Bismesylate · Euthrapie Brand of Almitrine Dimesilate · Servier Brand of Almitrine Dimesilate
Score:
#28 in Physiology
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#197 in Neurology
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#873 in Neuroscience
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#3829 in Biology
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- Additive effect on gas exchange of inhaled nitric oxide and intravenous almitrine bismesylate in the adult respiratory distress syndrome (Intensive Care Medicine, 1994)
- Dose-response curves of inhaled nitric oxide with and without intravenous almitrine in nitric oxide-responding patients with acute respiratory distress syndrome (Anesthesiology, 1995)
- Additive beneficial effects of the prone position, nitric oxide, and almitrine bismesylate on gas exchange and oxygen transport in acute respiratory distress syndrome (Critical Care Medicine, 1997)
- Effect of Almitrine on Ventilation-Perfusion Distribution in Adult Respiratory Distress Syndrome (The American review of respiratory disease, 1988)
- Severe Hypoxemia Associated With Liver Disease: Mayo Clinic Experience and the Experimental Use of Almitrine Bismesylate (1987)
- Long-lasting hyperventilation induced by almitrine: evidence for a specific effect on carotid and thoracic chemoreceptors. (European Journal of Pharmacology, 1980)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Almitrine Bismesylate
- Euthrapie Brand of Almitrine Dimesilate
- Servier Brand of Almitrine Dimesilate
- Vectarion
- Almitrine Monomesylate
- Almitrine Dimesylate
- Almitrine Bis(methanesulfonate)
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SMILESC=CCNC1=NC(=NC(=N1)N2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)NCC=C
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InChIKeyOBDOVFRMEYHSQB-UHFFFAOYSA-N
- Pubchem - ALMITRINE
- Wikipedia - almitrine
Almitrine (marketed as Duxil by Servier) is a diphenylmethylpiperazine derivative classified as a respiratory stimulant by the ATC. It enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease.
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