Weight | 537.576 g/mol |
---|---|
Formula | C28H42Cl2N4O2+2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 14 |
ambenonium (7648-98-8)
Mytelase · Ambenonium Chloride
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- Affinity of benzoquinonium and ambenonium derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution (Biochimica et Biophysica Acta, 1965)
- Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities. (Molecular Pharmacology, 1992)
- THE ANTAGONISM OF MUSCLE RELAXANTS AMBENONIUM AND METHOXYAMBENONIUM IN THE CAT (British journal of pharmacology and chemotherapy, 1960)
- Self-cancellation of drug properties as a mode of organ selectivity: the antimuscarinic effects of ambenonium. (Journal of Pharmacology and Experimental Therapeutics, 1985)
- AN INVESTIGATION OF THE STRUCTURE-ACTIVITY CORRELATIONS WITHIN A SERIES OF AMBENONIUM ANALOGS (Journal of Pharmacology and Experimental Therapeutics, 1958)
- Clinical Evaluation of Ambenonium (Mysuran) Chloride (Journal of Nervous and Mental Disease, 1956)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mytelase
- Ambenonium Chloride
-
SMILESCC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC2=CC=CC=C2Cl
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InChIKeyOMHBPUNFVFNHJK-UHFFFAOYSA-P
- Pubchem - ambenonium
- Wikipedia - ambenonium
Ambenonium (as ambenonium dichloride, trade name Mytelase) is a cholinesterase inhibitor used in the management of myasthenia gravis. It is classified as reversible.
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