Weight | 214.227 g/mol |
---|---|
Formula | C5H15N2O3PS |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 4 |
Aromatic Rings | 0 |
Rotatable Bonds | 7 |
amifostine (20537-88-6)
Ethyol · WR2721 · WR 2721
Score:
#558 in Biochemistry
,
#1678 in Biology
,
#1979 in Chemistry
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- Phase III Randomized Trial of Amifostine as a Radioprotector in Head and Neck Cancer (Journal of Clinical Oncology, 2000)
- Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer. (Journal of Clinical Oncology, 1996)
- Subcutaneous Administration of Amifostine During Fractionated Radiotherapy: A Randomized Phase II Study (Journal of Clinical Oncology, 2000)
- Amifostine: the first selective-target and broad-spectrum radioprotector. (Oncologist, 2007)
- Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head-and-neck cancer (International Journal of Radiation Oncology Biology Physics, 2002)
- Randomized Trial of Amifostine in Locally Advanced NonSmall-Cell Lung Cancer Patients Receiving Chemotherapy and Hyperfractionated Radiation: Radiation Therapy Oncology Group Trial 98-01 (Journal of Clinical Oncology, 2005)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ethyol
- WR2721
- WR 2721
- S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
- Gammaphos
- YM 08310
- YM08310
- Amifostine Monohydrate
- WR-2721
- APAETP
- Ethiofos
- NSC-296961
- Aminopropylaminoethylthiophosphate
- Aminopropylaminoethylthiophosphoric Acid
- Amifostine Disodium Salt
- Ethiofos Anhydrous
- YM-08310
- NSC296961
- Amifostine Monohydrochloride
- Amifostine Trihydrate
- Amifostine Anhydrous
- Aminopropyl Aminoethylthiophosphate
- NSC 296961
-
SMILESC(CN)CNCCSP(=O)(O)O
-
InChIKeyJKOQGQFVAUAYPM-UHFFFAOYSA-N
- Pubchem - amifostine
- Wikipedia - amifostine anhydrous
Amifostine (Ethiofos) is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents. It is marketed by Clinigen Group under the trade name Ethyol.
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