| Weight | 313.788 g/mol |
|---|---|
| Formula | C17H16ClN3O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
amoxapine (14028-44-5)
Asendin · Dfanyl · Asendis
Score:
#291 in Neuroscience
,
#376 in Biochemistry
,
#1327 in Biology
,
#1542 in Chemistry
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- Amoxapine versus amitriptyline combined with perphenazine in the treatment of psychotic depression. (American Journal of Psychiatry, 1990)
- Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline (Neuropharmacology, 1987)
- Amoxapine Overdose: Seizures and Fatalities (JAMA, 1983)
- Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters (British Journal of Pharmacology, 2000)
- GLC Analysis of Loxapine, Amoxapine, and Their Metabolites in Serum and Urine (Journal of Pharmaceutical Sciences, 1979)
- Double-blind comparison of amoxapine and imipramine in the treatment of depressed patients. (The Journal of Clinical Psychiatry, 1984)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Asendin
- Dfanyl
- Asendis
- 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
- CL67,772
- Amoxapine Wyeth Brand
- CL 67,772
- Lederle Brand of Amoxapine
- Desmethylloxapine
- CL-67,772
- Demolox
- Cyanamid Brand of Amoxapine
- Amoxapine Lederle Brand
- Wyeth Brand of Amoxapine
- Amoxapine Cyanamid Brand
-
SMILESC1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl
-
InChIKeyQWGDMFLQWFTERH-UHFFFAOYSA-N
- Pubchem - amoxapine
- Wikipedia - amoxapine
Amoxapine, sold under the brand name Asendin among others, is a tetracyclic antidepressant (TeCA), though it is often classified as a tricyclic antidepressant (TCA). It is the N-demethylated metabolite of loxapine. Amoxapine first received marketing approval in the United States in 1992 (approximately 30 to 40 years after most of the other TCAs were introduced in the United States).
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