| Weight | 393.468 g/mol |
|---|---|
| Formula | C21H19N3O3S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 5 |
amsacrine (51264-14-3)
AMSA · SN-11841 · NSC 141549
Score:
#351 in Biochemistry
,
#1467 in Chemistry
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- Quenching of DNA-ethidium fluorescence by amsacrine and other antitumor agents: a possible electron-transfer effect (Biochemistry, 1984)
- Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells. Evidence for two forms of the enzyme. (Journal of Biological Chemistry, 1987)
- The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (amsa) series. (European Journal of Cancer, 1974)
- Characterization of an amsacrine-resistant line of human leukemia cells: evidence for a drug-resistant form of topoisomerase II (Journal of Biological Chemistry, 1989)
- Identification of a point mutation in the topoisomerase II gene from a human leukemia cell line containing an amsacrine-resistant form of topoisomerase II. (Cancer Research, 1991)
- Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity. (Oncogene, 1993)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - AMSA
- SN-11841
- NSC 141549
- NSC-156303
- NSC249992
- NSC156303
- AMSA PD
- NSC 156303
- Cain Acridine
- AMSA P D
- NSC 249992
- SN 11841
- Amsidyl
- NSC-141549
- SN11841
- m-AMSA
- NSC-249992
- meta AMSA
- Cains Acridine
- Amsidine
- meta-AMSA
- Cain's Acridine
- NSC141549
- Amsacrina
- AMSA P-D
-
SMILESCOC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
-
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- Pubchem - amsacrine
- Wikipedia - amsacrine
Amsacrine (synonyms: m-AMSA, acridinyl anisidide) is an antineoplastic agent. It has been used in acute lymphoblastic leukemia.
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amsacrine
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