Alcohol · Amine · Antianginal · Antiarrhythmic agent · Antihypertensive agent · Antihypertensive agent · Bases (chemistry) · Beta blocker · Cardiovascular system drug · Chalcogenide · Cyclic compound · Drugs acting on the cardiovascular system · Five-membered ring · Organic compound · Pharmaceutical · Sulfide · Thiazole · Thioether · Thiophene

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Suppliers

• Sigma-Aldrich - Search for Arotinolol
• Fisher Scientific - Search for Arotinolol
• TCI - Search for Arotinolol

Most-cited Publications

• Effect of zonisamide on essential tremor: a pilot crossover study in comparison with arotinolol (Parkinsonism & Related Disorders, 2005)
• Preventive effects of carvedilol on nitrate tolerancea randomized, double-blind, placebo-controlled comparative study between carvedilol and arotinolol (Journal of the American College of Cardiology, 1998)
• BETA-3 ADRENERGIC AGONIST, BRL-26830A, AND ALPHA/BETA BLOCKER, AROTINOLOL, MARKEDLY INCREASE REGIONAL BLOOD FLOW IN THE BROWN ADIPOSE TISSUE IN ANESTHETIZED RATS (Japanese Circulation Journal-english Edition, 1992)
• A multicenter randomized crossover multiple-dose comparison study of arotinolol and propranolol in essential tremor (Parkinsonism & Related Disorders, 2003)
• Treatment of essential tremor with arotinolol (Neurology, 1988)
• Arotinolol is a weak partial agonist on 3-adrenergic receptors in brown adipocytes (Canadian Journal of Physiology and Pharmacology, 1998)

Safety

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Alternate Names

• S 596
• arotinolol, (+-)-isomer
• arotinolol hydrochloride
• S-596
• 2-(3'-tert-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-thienyl)thiazole hydrochloride
• SMILES
  CC(C)(C)NCC(CSC1=NC(=CS1)C2=CC=C(S2)C(=O)N)O
• InChIKey
  BHIAIPWSVYSKJS-UHFFFAOYSA-N

External Links

• Pubchem - Arotinolol
• Wikipedia - arotinolol
  Arotinolol (INN, marketed under the tradename Almarl) is a medication in the class of mixed alpha/beta blockers. It also acts as a 3 receptor agonist. A 1979 publication suggests arotinolol as having first been described in the scientific literature by Sumitomo Chemical as "-adrenergic blocking, antiarrhythmic compound S-596".

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