Weight | 351.368 g/mol |
---|---|
Formula | C19H20F3NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
benfluorex (23602-78-0)
S 780 · SE 780 · benfluorex hydrochloride
"What do you need help with?"
LabBot
- Sigma-Aldrich - benfluorex100.00 USD
- Fisher Scientific - Search for benfluorex
- TCI - Search for benfluorex
- Syndromes of Insulin Resistance in the Rat: Inducement by Diet and Amelioration with Benfluorex (Diabetes, 1993)
- Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus (Pharmacoepidemiology and Drug Safety, 2010)
- Benfluorex and Unexplained Valvular Heart Disease: A Case-Control Study (PLOS ONE, 2010)
- Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. (The Journal of Clinical Endocrinology and Metabolism, 1995)
- Fenfluramine-like cardiovascular side-effects of benfluorex. (European Respiratory Journal, 2009)
- Added benfluorex in obese insulin-requiring type 2 diabetes. (Diabetes & Metabolism, 1998)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - S 780
- SE 780
- benfluorex hydrochloride
- benfluorex hydrochloride, (+-)-isomer
- 1-(2-trifluoromethylphenyl)-2-(benzoyloxyethyl)aminopropane HCl
- 780 SE
- benfluramate
- benfluorex maleate
- JP 992
- benfluorex, methanesulfonate salt
-
SMILESCC(CC1=CC(=CC=C1)C(F)(F)F)NCCOC(=O)C2=CC=CC=C2
-
InChIKeyCJAVTWRYCDNHSM-UHFFFAOYSA-N
- Pubchem - benfluorex
- Wikipedia - benfluorex
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine patented and manufactured by a French pharmaceutical company Servier. Two clinical studies have shown it may improve glycemic control and decrease insulin resistance in people with poorly controlled type 2 diabetes. However, Servier is suspected of having marketed Mediator (benfluorex) at odds with the drug's medical properties.
Suppliers
Most-cited Publications
Areas of Application
Safety
Trends
Alternate Names
External Links
Synthesis
benzoic acid
+
N-(2-Chloroethyl)-alpha-methyl-m-trifluoromethylphenethylamine
(Ester from carboxilic acid(SN2))
2-Aminoethyl benzoate
+
Reactant
(Alkylation of primary amines)
BENZOTRIFLUORIDE
+
Reactant
(Friedel-Crafts alkylation)
Reactant
+
NORFENFLURAMINE
(Reductive amination)
Similar Compounds
Diethylene glycol dibenzoate
(120-55-8)
11 alternate names
3 suppliers
Centralite
(85-98-3)
11 alternate names
3 suppliers
2,3-Dimethyl-2,3-diphenylbutane
(1889-67-4)
11 alternate names
3 suppliers
Trifluperidol
(749-13-3)
11 alternate names
3 suppliers
CINNAMYL ANTHRANILATE
(87-29-6)
11 alternate names
3 suppliers
Homosalate
(118-56-9)
11 alternate names
3 suppliers
BUPROFEZIN
(953030-84-7, 69327-76-0)
11 alternate names
3 safety hazards
3 suppliers
DICUMYL PEROXIDE
(80-43-3)
11 alternate names
4 safety hazards
3 suppliers
Chalcone
(614-47-1, 94-41-7)
11 alternate names
3 suppliers
PHENETHYL ANTHRANILATE
(133-18-6)
11 alternate names
3 suppliers
1,3-diphenylpropan-1-one
(1083-30-3)
11 alternate names
3 suppliers
N-Fluorobenzenesulfonimide
(133745-75-2)
11 alternate names
3 suppliers
530-44-9
(530-44-9)
11 alternate names
3 suppliers
Mefenacet
(73250-68-7)
11 alternate names
3 safety hazards
3 suppliers
BENALAXYL
(71626-11-4)
11 alternate names
2 safety hazards
3 suppliers
ARAMITE
(140-57-8)
11 alternate names
2 safety hazards
3 suppliers
Chlorfenapyr
(122453-73-0)
11 alternate names
5 safety hazards
3 suppliers
Etoxazole
(153233-91-1)
11 alternate names
2 safety hazards
3 suppliers
2778-42-9
(2778-42-9)
11 alternate names
3 suppliers
o-Isopropylphenyl diphenyl phosphate
(93925-53-2, 64532-94-1)
11 alternate names
3 suppliers
BENZYL SALICYLATE
(118-58-1)
11 alternate names
3 suppliers
BENZPHETAMINE HYDROCHLORIDE
(5411-22-3)
11 alternate names
3 suppliers
Octabenzone
(1843-05-6)
11 alternate names
3 suppliers
CITRUS RED 2
(6358-53-8)
11 alternate names
1 safety hazard
3 suppliers
Phenoxybenzamine hydrochloride
(63-92-3)
11 alternate names
2 safety hazards
3 suppliers
Citrus Red
(6358-53-8)
11 alternate names
1 safety hazard
3 suppliers
Solvent red 80
(6358-53-8)
11 alternate names
1 safety hazard
3 suppliers
BENZOIN
(119-53-9, 8050-35-9, 9000-72-0, 9000-05-9, 579-44-2)
11 alternate names
3 suppliers
BENZYL CINNAMATE
(103-41-3)
11 alternate names
3 suppliers
WLN: R1U1VO1R
(103-41-3)
11 alternate names
3 suppliers
DIPHENYL CARBONATE
(102-09-0)
11 alternate names
2 safety hazards
3 suppliers
103-41-3
(103-41-3)
11 alternate names
3 suppliers
DESMEDIPHAM
(13684-56-5)
11 alternate names
4 safety hazards
3 suppliers
DIBENAMINE
(51-50-3)
11 alternate names
3 suppliers
Dibenzylideneacetone
(538-58-9, 35225-79-7)
11 alternate names
3 suppliers
Piperlongumine
(20069-09-4)
11 alternate names
3 suppliers
Benzyl phenylacetate
(102-16-9)
11 alternate names
3 suppliers
Clobenzorex
(76553-22-5, 13364-32-4)
11 alternate names
3 suppliers
PYROLAN
(87-47-8)
11 alternate names
3 suppliers
Atomoxetine HCL
(82248-59-7)
11 alternate names
3 suppliers
Pyriproxyfen
(126040-81-1, 95737-68-1)
11 alternate names
2 safety hazards
3 suppliers
Methyl yellow
(60-11-7)
11 alternate names
3 safety hazards
3 suppliers
CHLORSULFURON
(112143-77-8, 64902-72-3)
11 alternate names
2 safety hazards
3 suppliers
OXYCARBOXIN
(5259-88-1)
11 alternate names
1 safety hazard
3 suppliers
2971-38-2
(2971-38-2)
11 alternate names
3 suppliers
1,8-Naphthalic anhydride
(81-84-5)
11 alternate names
3 suppliers
4,4'-Sulfonyldiphenol
(80-09-1)
11 alternate names
3 suppliers
N-Benzyl-N-ethylaniline
(92-59-1)
11 alternate names
3 suppliers
Assert
(69969-22-8)
11 alternate names
3 suppliers
adiphenine
(64-95-9)
11 alternate names
3 suppliers
Mepivacaine hydrochloride
(1722-62-9)
11 alternate names
3 suppliers
Thiocarbanilide
(102-08-9)
11 alternate names
3 suppliers
Etofenprox
(80844-07-1)
11 alternate names
4 safety hazards
3 suppliers
CAS Directory