Bergapten (484-20-8)

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Suppliers

• 

  50 mg
  $45.00

  250 mg
  $50.00

  1 g
  $75.00

  10 g
  $175.00

  25 g
  $375.00

Most-cited Publications

• Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen. (Biochemistry, 1982)
• 5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties (Nature, 1980)
• 5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis (British Journal of Dermatology, 1979)
• 5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation (Carcinogenesis, 1981)
• Content of CYP3A4 inhibitors, naringin, naringenin and bergapten in grapefruit and grapefruit juice products (Pharmaceutica Acta Helvetiae, 2000)
• 5-Methoxypsoralen (Bergapten) for photochemotherapy: Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation (Journal of The American Academy of Dermatology, 1988)

Areas of Application

Safety

• Request a Demo
  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H341: Suspected of causing genetic defects
  Warning Germ cell mutagenicity - Category 2
• H361: Suspected of damaging fertility or the unborn child
  Warning Reproductive toxicity - Category 2
• H373: Causes damage to organs through prolonged or repeated exposure
  Warning Specific target organ toxicity, repeated exposure - Category 2

Trends

Alternate Names

• Pentaderm
• 5-methoxypsoralen
• SMILES
  COC1=C2C=CC(=O)OC2=CC3=C1C=CO3
• InChIKey
  BGEBZHIAGXMEMV-UHFFFAOYSA-N

External Links

• Pubchem - Bergapten
• Wikipedia - bergapten
  Bergapten (5-methoxypsoralen) is a psoralen (also known as furocoumarins) found in bergamot essential oil, in other citrus essential oils, and in grapefruit juice. It is the chemical in bergamot oil that causes phototoxicity. Bergapten-free bergamot essential oil or synthetics are now used in perfumery.

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Bergapten

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