Weight | 242.274 g/mol |
---|---|
Formula | C15H14O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
beta-Lapachone (4707-32-8)
ARQ 501
Score:
#77 in Molecular and cellular biology
,
#2188 in Biochemistry
,
#5634 in Chemistry
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- beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin. (Journal of Biological Chemistry, 1993)
- POTENT INHIBITION OF TUMOR SURVIVAL IN VIVO BY BETA -LAPACHONE PLUS TAXOL : COMBINING DRUGS IMPOSES DIFFERENT ARTIFICIAL CHECKPOINTS (Proceedings of the National Academy of Sciences of the United States of America, 1999)
- Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells. (Molecular Medicine, 1999)
- .beta.-Lapachone: synthesis of derivatives and activities in tumor models (Journal of Medicinal Chemistry, 1984)
- Effect of beta-lapachone on superoxide anion and hydrogen peroxide production in Trypanosoma cruzi. (Biochemical Journal, 1978)
- Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1. (Cancer Biology & Therapy, 2005)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ARQ 501
-
SMILESCC1(CCC2=C(O1)C3=CC=CC=C3C(=O)C2=O)C
-
InChIKeyQZPQTZZNNJUOLS-UHFFFAOYSA-N
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