| Weight | 307.434 g/mol |
|---|---|
| Formula | C18H29NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 11 |
betaxolol (63659-18-7)
Betoptic · Kerlone · Betaxolol Hydrochloride
Score:
#2598 in Biology
,
#3244 in Chemistry
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- A double-masked, randomized 1-year study comparing dorzolamide (trusopt), timolol, and betaxolol (Archives of Ophthalmology, 1995)
- In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent (Brain Research, 1997)
- Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. (American Journal of Ophthalmology, 1995)
- Topically applied betaxolol attenuates NMDA-induced toxicity to ganglion cells and the effects of ischaemia to the retina. (Experimental Eye Research, 1999)
- Effects of Topical Betaxolol, Timolol, and Placebo on Pulmonary Function in Asthmatic Bronchitis (American Journal of Ophthalmology, 1984)
- The -adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: comparison with betaxolol (Experimental Eye Research, 2003)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Betoptic
- Kerlone
- Betaxolol Hydrochloride
- Kerlon
- SL 75212
- ALO 1401 02
- Betoptima
- ALO140102
- Betaxolol Alcon
- SL-75212
- ALO-1401-02
- Oxodal
- SL75212
-
SMILESCC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
-
InChIKeyNWIUTZDMDHAVTP-UHFFFAOYSA-N
- Pubchem - betaxolol
- Wikipedia - betaxolol
Betaxolol (trade names Betoptic, Betoptic S, Lokren, Kerlone) is a selective beta1 receptor blocker used in the treatment of hypertension and glaucoma. Being selective for beta1 receptors, it typically has fewer systemic side effects than non-selective beta-blockers, for example, not causing bronchospasm (mediated by beta2 receptors) as timolol may. Betaxolol also shows greater affininty for beta1 receptors than metoprolol.
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Synthesis
Cyclopropylmethanol
+
Reactant
(Williamson ether)
7695-63-8
+
Reactant
(Friedel-Crafts alkylation)
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