| Weight | 456.711 g/mol |
|---|---|
| Formula | C30H48O3 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
betulinic acid (472-15-1)
betulic acid · 3-epi-betulinic acid
Score:
#2037 in Biochemistry
,
#4254 in Biology
,
#5365 in Chemistry
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- Sigma-Aldrich - betulinic acid41.90 - 332.00 USD
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- Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. (Nature Medicine, 1995)
- Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid (Journal of Biological Chemistry, 1998)
- Betulinic Acid Triggers CD95 (APO-1/Fas)- and p53-independent Apoptosis via Activation of Caspases in Neuroectodermal Tumors (Cancer Research, 1997)
- Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells (Cancer Letters, 2002)
- Betulinic acid and its derivatives: A review on their biological properties (Current Medicinal Chemistry, 2005)
- Anti-AIDS Agents, 11. Betulinic Acid and Platanic Acid as Anti-HIV Principles from Syzigium claviflorum, and the Anti-HIV Activity of Structurally Related Triterpenoids (Journal of Natural Products, 1994)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - betulic acid
- 3-epi-betulinic acid
-
SMILESCC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)O
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InChIKeyQGJZLNKBHJESQX-UHFFFAOYSA-N
- Pubchem - betulinic acid
- Wikipedia - betulinic acid
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name, but also the ber tree (Ziziphus mauritiana), selfheal (Prunella vulgaris), the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas, a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum), flowering quince (Pseudocydonia sinensis, former Chaenomeles sinensis KOEHNE), rosemary, and Pulsatilla chinensis.
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betulinic acid
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