| Weight | 367.512 g/mol |
|---|---|
| Formula | C23H30FN3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
Blonanserin (132810-10-7)
Score:
#217 in Neurology
,
#990 in Neuroscience
,
#4333 in Biology
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#5464 in Chemistry
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- Blonanserin: A Review of its Use in the Management of Schizophrenia (CNS Drugs, 2010)
- The efficacy and safety of blonanserin compared with haloperidol in acute-phase schizophrenia: a randomized, double-blind, placebo-controlled, multicentre study. (CNS Drugs, 2009)
- Efficacy and Tolerability of Blonanserin in the Patients With Schizophrenia: A Randomized, Double-blind, Risperidone-Compared Trial (Clinical Neuropharmacology, 2010)
- Blonanserin for schizophrenia: Systematic review and meta-analysis of double-blind, randomized, controlled trials (Journal of Psychiatric Research, 2013)
- Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5-HT)2A and DA D2 antagonism and 5-HT1A partial agonism. (Journal of Neurochemistry, 2014)
- Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex. (European Journal of Pharmacology, 2011)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCN1CCN(CC1)C2=NC3=C(CCCCCC3)C(=C2)C4=CC=C(C=C4)F
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InChIKeyXVGOZDAJGBALKS-UHFFFAOYSA-N
- Pubchem - Blonanserin
- Wikipedia - blonanserin
Blonanserin, sold under the brand name Lonasen, is a relatively new atypical antipsychotic (approved by PMDA in January 2008) commercialized by Dainippon Sumitomo Pharma in Japan and Korea for the treatment of schizophrenia. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As with many second-generation (atypical) antipsychotics it is significantly more efficacious in the treatment of the negative symptoms of schizophrenia compared to first-generation (typical) antipsychotics such as haloperidol.
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Blonanserin
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