| Weight | 384.245 g/mol |
|---|---|
| Formula | C19H25BN4O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
Bortezomib (179324-69-7)
Score:
#182 in Biochemistry
,
#748 in Biology
,
#817 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Bortezomib25.75 USD
- Fisher Scientific - Search for Bortezomib
- TCI - Search for Bortezomib
- A phase 2 study of Bortezomib in relapsed, refractory myeloma (The New England Journal of Medicine, 2003)
- Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma (The New England Journal of Medicine, 2005)
- Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. (The New England Journal of Medicine, 2008)
- A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma (British Journal of Haematology, 2004)
- Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. (Blood, 2010)
- Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study (Lancet Oncology, 2011)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESB(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
-
InChIKeyGXJABQQUPOEUTA-UHFFFAOYSA-N
- Pubchem - Bortezomib
- Wikipedia - bortezomib
Bortezomib (BAN, INN and USAN; marketed as Velcade by Millennium Pharmaceuticals; Neomib by Getwell and Bortecad by Cadila Healthcare) is an anti-cancer drug and the first therapeutic proteasome inhibitor to be used in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Synthesis
Pyrazinamide
+
Reactant
(Alkylation of primary amines)
2-Pyrazinecarbonyl chloride
+
Reactant
(Schotten-Baumann amide from acid)
benzene
+
Reactant
(Friedel-Crafts alkylation)
Similar Compounds
Halofenozide
(112226-61-6)
1 alternate name
1 safety hazard
3 suppliers
CHLOROPROPYLATE
(5836-10-2)
1 alternate name
3 suppliers
2618-77-1
(2618-77-1)
1 alternate name
3 suppliers
Bromopropylate
(18181-80-1)
1 alternate name
3 suppliers
Octocrylene
(6197-30-4)
1 alternate name
3 suppliers
Talinolol
(57460-41-0)
1 alternate name
3 suppliers
2-Ethylhexyl diphenyl phosphate
(1241-94-7)
1 alternate name
2 safety hazards
3 suppliers
Octabenzone
(1843-05-6)
1 alternate name
3 suppliers
adiphenine
(64-95-9)
1 alternate name
3 suppliers
Benzyl butyl phthalate
(85-68-7)
1 alternate name
4 safety hazards
3 suppliers
CHLOROBENZILATE
(510-15-6)
1 alternate name
4 safety hazards
3 suppliers
DIPHENAMID
(957-51-7)
1 alternate name
1 safety hazard
3 suppliers
ISODECYL DIPHENYL PHOSPHATE
(29761-21-5)
1 alternate name
3 suppliers
FLUTOLANIL
(66332-96-5)
1 alternate name
1 safety hazard
3 suppliers
Perbutyl MA
(2155-71-7)
1 alternate name
3 suppliers
Octyl diphenyl phosphate
(115-88-8)
1 alternate name
3 suppliers
Paclobutrazol
(76738-62-0, 66346-04-1)
1 alternate name
3 suppliers
DEHP
(15495-94-0, 8033-53-2, 117-81-7)
1 alternate name
6 safety hazards
3 suppliers
DIISONONYL PHTHALATE
(28553-12-0, 68515-48-0)
1 alternate name
3 suppliers
DIISODECYL PHTHALATE
(26761-40-0, 89-16-7, 68515-49-1)
1 alternate name
1 safety hazard
3 suppliers
DIISOBUTYL PHTHALATE
(84-69-5)
1 alternate name
3 safety hazards
3 suppliers
Diisooctyl phthalate
(27554-26-3)
1 alternate name
3 suppliers
Bifenazate
(149877-41-8)
1 alternate name
5 safety hazards
3 suppliers
Cyhalofop-butyl
(122008-85-9)
1 alternate name
2 safety hazards
3 suppliers
Isoxaben
(82558-50-7)
1 alternate name
3 safety hazards
3 suppliers
BIS(2-ETHYLHEXYL) TEREPHTHALATE
(6422-86-2)
1 alternate name
3 suppliers
NAPTALAM
(132-66-1)
1 alternate name
3 suppliers
Phorazetim
(4104-14-7)
1 alternate name
3 safety hazards
3 suppliers
PHOSACETIM
(4104-14-7)
1 alternate name
3 safety hazards
3 suppliers
Phosazetim
(4104-14-7)
1 alternate name
3 safety hazards
3 suppliers
Oxybutynin chloride
(1508-65-2, 1207344-05-5)
1 alternate name
3 suppliers
DESMEDIPHAM
(13684-56-5)
1 alternate name
4 safety hazards
3 suppliers
CYCLOPENTOLATE HYDROCHLORIDE
(5870-29-1)
1 alternate name
3 suppliers
PROPAFENONE HYDROCHLORIDE
(34183-22-7, 107381-35-1, 107381-36-2)
1 alternate name
3 suppliers
Dinopol ido
(1330-96-7)
1 alternate name
3 suppliers
TRIADIMEFON
(43121-43-3)
1 alternate name
2 safety hazards
3 suppliers
Thiophanate-methyl
(23564-05-8)
1 alternate name
5 safety hazards
3 suppliers
Tebuconazole
(80443-41-0, 107534-96-3)
1 alternate name
6 safety hazards
3 suppliers
3-Quinuclidinyl benzilate
(6581-06-2)
1 alternate name
3 suppliers
(R)-(-)-3-Quinuclidinyl benzilate
(62869-69-6)
1 alternate name
3 suppliers
CHLOROXURON
(1982-47-4)
1 alternate name
3 suppliers
FLUAZIFOP-BUTYL
(86334-14-7, 69806-50-4)
1 alternate name
3 safety hazards
3 suppliers
3-Pyridinecarboxylicacid, 2-[1-[2-[[(3,5-difluorophenyl)amino]carbonyl]hydrazinylidene]ethyl]-
(109293-97-2)
1 alternate name
3 suppliers
DIPHENHYDRAMINE HYDROCHLORIDE
(147-24-0)
1 alternate name
3 safety hazards
3 suppliers
Bisphenol B
(77-40-7)
1 alternate name
3 suppliers
Butyl 2-ethylhexyl phthalate
(85-69-8)
1 alternate name
3 suppliers
793-24-8
(793-24-8)
1 alternate name
4 safety hazards
3 suppliers
Thiophanate
(23564-06-9)
1 alternate name
3 suppliers
Michler's ketone
(90-94-8)
1 alternate name
3 safety hazards
3 suppliers
BUTYL CYCLOHEXYL PHTHALATE
(84-64-0)
1 alternate name
3 suppliers
dioxybenzone
(131-53-3)
1 alternate name
3 suppliers
Nafenopin
(3771-19-5)
1 alternate name
3 suppliers
THONZYLAMINE HYDROCHLORIDE
(63-56-9)
1 alternate name
3 suppliers
spiperone
(749-02-0)
1 alternate name
3 suppliers
LOBELINE HYDROCHLORIDE
(134-63-4)
1 alternate name
3 suppliers
Methadone hydrochloride
(1095-90-5)
1 alternate name
3 suppliers
Dioctyl phthalate
(117-84-0, 8031-29-6)
1 alternate name
2 safety hazards
3 suppliers
Bortezomib
CAS Directory
