| Weight | 551.625 g/mol |
|---|---|
| Formula | C27H29N5O6S |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 10 |
Bosentan (147536-97-8)
Score:
#908 in Biochemistry
,
#2406 in Biology
,
#2993 in Chemistry
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- BOSENTAN THERAPY FOR PULMONARY ARTERIAL HYPERTENSION (The New England Journal of Medicine, 2002)
- Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo- controlled study (The Lancet, 2001)
- Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. (Journal of Pharmacology and Experimental Therapeutics, 1994)
- Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial (The Lancet, 2008)
- Bosentan Therapy in Patients With Eisenmenger Syndrome A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study (Circulation, 2006)
- Digital Ulcers in Systemic Sclerosis Prevention by Treatment With Bosentan, an Oral Endothelin Receptor Antagonist (Arthritis & Rheumatism, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
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- Pubchem - Bosentan
- Wikipedia - bosentan anhydrous
Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH). It is licensed in the United States, the European Union and other countries by Actelion Pharmaceuticals for the management of PAH under the trade name Tracleer.
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Bosentan
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