Score: #381 in Neuroscience , #1732 in Biology , #2043 in Chemistry

  Alcohol · Analgesic · Antiarrhythmic agent · Delta-opioid antagonist · Drugs acting on the cardiovascular system · Drugs acting on the nervous system · Drugs by psychological effect · Ether · Euphoriant · Kappa antagonist · Mu-opioid agonist · Nociceptin receptor agonist · Nociceptin receptor antagonist · Opioid antagonist · Opioid receptor ligand · Opioid · Organic compound · Oripavine · Pharmaceutical · Psychoactive drug · Psychoactive drugs by mechanism of action · Semisynthetic opioid · Sodium channel blocker · Synthetic opioid

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Suppliers

• Sigma-Aldrich - Search for buprenorphine
• Fisher Scientific - Search for buprenorphine
• TCI - Search for buprenorphine

Most-cited Publications

• Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence (Cochrane Database of Systematic Reviews, 2014)
• Clinical pharmacology of buprenorphine: ceiling effects at high doses. (Clinical Pharmacology & Therapeutics, 1994)
• A comparison of levomethadyl acetate, buprenorphine, and methadone for opioid dependence. (The New England Journal of Medicine, 2000)
• Prediction in drug abuse: cocaine interactions with alcohol and buprenorphine. (The British journal of psychiatry. Supplement, 1993)
• Human Pharmacology and Abuse Potential of the Analgesic Buprenorphine: A Potential Agent for Treating Narcotic Addiction (Archives of General Psychiatry, 1978)
• Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone) (Pain Practice, 2008)

Areas of Application

Safety

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  Predict GHS Hazards for Any Chemical in silico.
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Trends

Alternate Names

• Buprenex
• Buprenorphine Hydrochloride
• Subutex
• Temgesic
• RX6029M
• Buprex
• Temgsic
• 6029M
• 6029-M
• Essex Brand of Buprenorphine Hydrochloride
• Schering-Plough Brand of Buprenorphine Hydrochloride
• Buprenorphine Grnenthal Brand
• Reckitt Brand of Buprenorphine Hydrochloride
• Reckitt and Colman Brand 1 of Buprenorphine Hydrochloride
• RX-6029-M
• Key Brand of Buprenorphine Hydrochloride
• RX 6029 M
• Prefin
• Schering Plough Brand of Buprenorphine Hydrochloride
• 6029 M
• Reckitt Benckiser Brand of Buprenorphine Hydrochloride
• Grnenthal Brand of Buprenorphine
• Reckitt and Colman Brand 2 of Buprenorphine Hydrochloride
• Grnenthal Brand of Buprenorphine Hydrochloride
• SMILES
  CC(C)(C)C(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
• InChIKey
  RMRJXGBAOAMLHD-UHFFFAOYSA-N

External Links

• Pubchem - buprenorphine
• Wikipedia - buprenorphine
  Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain. It can be used under the tongue, by injection, as a skin patch, or as an implant. When used for opioid addiction it is recommended that a health care provider observe the person while they take the medication.

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