| Weight | 359.354 g/mol |
|---|---|
| Formula | C15H22FN3O6 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
CAPECITABINE (154361-50-9)
Score:
#111 in Biochemistry
,
#486 in Biology
,
#509 in Chemistry
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- Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer (The New England Journal of Medicine, 2006)
- Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer (The New England Journal of Medicine, 2008)
- Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer (Journal of Clinical Oncology, 2005)
- Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue (European Journal of Cancer, 1998)
- Superior Survival With Capecitabine Plus Docetaxel Combination Therapy in Anthracycline-Pretreated Patients With Advanced Breast Cancer: Phase III Trial Results (Journal of Clinical Oncology, 2002)
- Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III Study (Journal of Clinical Oncology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O
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InChIKeyGAGWJHPBXLXJQN-UHFFFAOYSA-N
- Pubchem - CAPECITABINE
- Wikipedia - capecitabine
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. For breast cancer it is often used together with docetaxel. It is taken by mouth.
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