Weight | 226.232 g/mol |
---|---|
Formula | C10H14N2O4 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 5 |
Aromatic Rings | 1 |
Rotatable Bonds | 4 |
carbidopa (28860-95-9)
Lodosyn · MK 486 · Methyldopahydrazine
Score:
#85 in Neurology
,
#431 in Neuroscience
,
#1982 in Biology
,
#2413 in Chemistry
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- Augmentation of the restless legs syndrome with carbidopa/levodopa. (Sleep, 1996)
- Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study (Lancet Neurology, 2014)
- Immediate-release and controlled-release carbidopa/levodopa in PD A 5-year randomized multicenter study (Neurology, 1999)
- Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: The STRIDEPD study (Annals of Neurology, 2010)
- Comparison of Immediate-Release and Controlled Release Carbidopa/Levodopa in Parkinsons Disease (European Neurology, 1997)
- Pergolide and carbidopa/levodopa treatment of the restless legs syndrome and periodic leg movements in sleep in a consecutive series of patients (Sleep, 1996)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lodosyn
- MK 486
- Methyldopahydrazine
- MK 485
- MK485
- Carbidopa, (S)-Isomer
- MK486
- MK-485
- MK-486
- Carbidopa, (R)-Isomer
- Lodosin
-
SMILESCC(CC1=CC(=C(C=C1)O)O)(C(=O)O)NN
-
InChIKeyTZFNLOMSOLWIDK-UHFFFAOYSA-N
- Pubchem - carbidopa
- Wikipedia - carbidopa
Carbidopa (Lodosyn) is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the bloodbrain barrier for central nervous system effect.
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