| Weight | 214.052 g/mol |
|---|---|
| Formula | C5H9Cl2N3O2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
carmustine (154-93-8)
BCNU · BiCNU · FIVB
Score:
#99 in Neuroscience
,
#500 in Biology
,
#527 in Chemistry
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- Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. (Journal of Neurosurgery, 1978)
- A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma (Neuro-oncology, 2003)
- Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: Report of Radiation Therapy Oncology Group 93-05 protocol (International Journal of Radiation Oncology Biology Physics, 2004)
- Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarrazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report (International Journal of Radiation Oncology Biology Physics, 1990)
- Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034 (Journal of Clinical Oncology, 2009)
- Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study. (Neurosurgery, 1997)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H300: Fatal if swallowed
Danger Acute toxicity, oral - Category 1, 2 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - BCNU
- BiCNU
- FIVB
- 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
- Nitrumon
- N,N'-Bis(2-Chloroethyl)-N-Nitrosourea
-
SMILESC(CCl)NC(=O)N(CCCl)N=O
-
InChIKeyDLGOEMSEDOSKAD-UHFFFAOYSA-N
- Pubchem - carmustine
- Wikipedia - carmustine
Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a medication used mainly for chemotherapy It is a nitrogen mustard -chloro-nitrosourea compound used as an alkylating agent.
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carmustine
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