| Weight | 189.211 g/mol |
|---|---|
| Formula | C8H15NO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
castanospermine (79831-76-8)
Score:
#1913 in Biochemistry
,
#4080 in Biology
,
#5143 in Chemistry
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- Castanospermine, A 1,6,7,8-tetrahydroxyoctahydroindolizine alkaloid, from seeds of Castanospermum australe (Phytochemistry, 1981)
- Inhibition of Experimental Metastasis by Castanospermine in Mice: Blockage of Two Distinct Stages of Tumor Colonization by Oligosaccharide Processing Inhibitors (Cancer Research, 1986)
- Castanospermine, a tetrahydroxylated alkaloid that inhibits -glucosidase and -glucocerebrosidase (Archives of Biochemistry and Biophysics, 1983)
- Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine (Proceedings of the National Academy of Sciences of the United States of America, 1987)
- Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin (Biochemistry, 1983)
- Castanospermine, a Potent Inhibitor of Dengue Virus Infection In Vitro and In Vivo (Journal of Virology, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN2CC(C(C(C2C1O)O)O)O
-
InChIKeyJDVVGAQPNNXQDW-UHFFFAOYSA-N
- Pubchem - castanospermine
- Wikipedia - castanospermine
Castanospermine is an indolizidine alkaloid first isolated from the seeds of Castanospermum australe. It is a potent inhibitor of some glucosidase enzymes and has antiviral activity in vitro and in mouse models. Castanospermine was a lead to celgosivir.
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castanospermine
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