| Weight | 480.572 g/mol |
|---|---|
| Formula | C19H24N6O5S2 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
cefepime (88040-23-7)
Maxipime · cefepime hydrochloride · BMY-28142
Score:
#406 in Microbiology
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#3200 in Biology
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#4002 in Chemistry
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- Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections (International Journal of Antimicrobial Agents, 2008)
- Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae (Antimicrobial Agents and Chemotherapy, 2001)
- Efficacy and safety of cefepime: a systematic review and meta-analysis. (Lancet Infectious Diseases, 2007)
- Cefepime versus Imipenem-Cilastatin for Treatment of Nosocomial Pneumonia in Intensive Care Unit Patients: a Multicenter, Evaluator-Blind, Prospective, Randomized Study (Antimicrobial Agents and Chemotherapy, 2003)
- A Randomized, Double-blind Clinical Trial Comparing Cefepime Plus Metronidazole With Imipenem-Cilastatin in the Treatment of Complicated Intra-abdominal Infections (Archives of Surgery, 1997)
- Pharmacodynamics of cefepime in patients with Gram-negative infections (Journal of Antimicrobial Chemotherapy, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Maxipime
- cefepime hydrochloride
- BMY-28142
- Axpim
- cefepim
- Quadrocef
- BMY 28142
- Bristol-Myers brand of cefepime dihydrochloride
- Bristol-Myers Squibb brand of cefepime dihydrochloride
- Elan brand of cefepime dihydrochloride
-
SMILESC[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-]
-
InChIKeyHVFLCNVBZFFHBT-UHFFFAOYSA-N
- Pubchem - cefepime
- Wikipedia - cefepime
Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other -lactam antibiotics.
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