| Weight | 489.575 g/mol |
|---|---|
| Formula | C20H38Cl2N2O3S2 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
Cevimeline hydrochloride (153504-70-2)
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- Sigma-Aldrich - Cevimeline hydrochloride107.00 - 414.00 USD
- Fisher Scientific - Search for Cevimeline hydrochloride
- TCI - Search for Cevimeline hydrochloride
- (+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate (SNI-2011, cevimeline hydrochloride) induces saliva and tear secretions in rats and mice: the role of muscarinic acetylcholine receptors. (Japanese Journal of Pharmacology, 1998)
- The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjgrens syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study (Clinical Rheumatology, 2008)
- Effects of Pilocarpine Hydrochloride and Cevimeline on Submandibular/ Sublingual Salivation in Rat Xerostomia Model Produced by X-Ray Irradiation (Drug Research, 2011)
- [Clinical significance of cevimeline hydrochloride in the treatment of dry mouth in patients with Sjgren's syndrome]. (Japanese journal of clinical immunology, 2004)
- [The effectiveness of cevimeline hydrochloride on dry cough in Sjgren's syndrome]. (Japanese journal of clinical immunology, 2004)
- Effects of chronic administration of Cevimeline hydrochloride on salivary secretion in Balb/cA mice (Oral Therapeutics and Pharmacology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1OC2(CN3CCC2CC3)CS1.CC1OC2(CN3CCC2CC3)CS1.O.Cl.Cl
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InChIKeyZSTLCHCDLIUXJE-UHFFFAOYSA-N
- Pubchem - Cevimeline hydrochloride
- Wikipedia - cevimeline hydrochloride
Cevimeline (trade name Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors. It is used in the treatment of dry mouth and especially associated with Sjgren's syndrome.
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