| Weight | 423.205 g/mol |
|---|---|
| Formula | C15H16Cl2N2O8 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 10 |
CHLORAMPHENICOL SUCCINATE (982-57-0, 3544-94-3)
chloramphenicol sodium succinate · chloramphenicol succinate sodium · chloramphenicol monosuccinate
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- Profound Cardioprotection With Chloramphenicol Succinate in the Swine Model of Myocardial Ischemia-Reperfusion Injury (Circulation, 2010)
- Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate. (Clinical Pharmacokinectics, 1984)
- Pharmacokinetics of chloramphenicol and chloramphenicol succinate in infants and children (The Journal of Pediatrics, 1981)
- Evaluation of chloramphenicol acid succinate therapy of induced typhoid fever and rocky mountain spotted fever. (The New England Journal of Medicine, 1970)
- Relative bioavailability of intravenouschloramphenicol succinate and oral chloramphenicol palmitate in infants and children (The Journal of Pediatrics, 1981)
- Bioavailability and clearance of chloramphenicol after intravenous chloramphenicol succinate (Clinical Pharmacology & Therapeutics, 1981)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - chloramphenicol sodium succinate
- chloramphenicol succinate sodium
- chloramphenicol monosuccinate
- chloramphenicol hemisuccinate
- levomycetin succinate
-
SMILESC1=CC(=CC=C1C(C(COC(=O)CCC(=O)O)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
-
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- Pubchem - CHLORAMPHENICOL SUCCINATE
- Wikipedia - chloramphenicol succinate
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever.
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Synthesis
Reactant
+
4-Chloronitrobenzene
(Grignard alcohol)
NITROBENZENE
+
Reactant
(Friedel-Crafts alkylation)
2,2-Dichloroacetamide
+
Reactant
(Alkylation of primary amines)
succinic acid
+
Reactant
(Ester from carboxilic acid(SN2))
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
Similar Compounds
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