Weight | 288.182 g/mol |
---|---|
Formula | C11H15Cl2N5 |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
Chlorproguanil (537-21-3)
lapudrine · unspecified HCl of chlorproguanil · mono-HCl of chlorproguanil
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- Molecular Markers for Failure of Sulfadoxine-Pyrimethamine and Chlorproguanil-Dapsone Treatment of Plasmodium falciparum Malaria (The Journal of Infectious Diseases, 2002)
- Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania. (The Lancet, 2001)
- Molecular Evidence of Greater Selective Pressure for Drug Resistance Exerted by the Long-Acting Antifolate Pyrimethamine/Sulfadoxine Compared with the Shorter-Acting Chlorproguanil/Dapsone on Kenyan Plasmodium falciparum (The Journal of Infectious Diseases, 2000)
- Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial (The Lancet, 2004)
- Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria. (Antimicrobial Agents and Chemotherapy, 1997)
- In Vivo Selection for a Specific Genotype of Dihydropteroate Synthetase of Plasmodium falciparum by Pyrimethamine-Sulfadoxine but Not Chlorproguanil-Dapsone Treatment (The Journal of Infectious Diseases, 1998)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - lapudrine
- unspecified HCl of chlorproguanil
- mono-HCl of chlorproguanil
-
SMILESCC(C)N=C(N)N=C(N)NC1=CC(=C(C=C1)Cl)Cl
-
InChIKeyISZNZKHCRKXXAU-UHFFFAOYSA-N
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N'-Propan-2-ylmethanediimine
+
Reactant
(Thiourea)
Reactant
+
ISOPROPYLAMINE
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