| Weight | 358.46 g/mol |
|---|---|
| Formula | C16H26N2O5S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 11 |
Cilastatin (82009-34-5)
Cilastatin Sodium · MK-791 · MK 0791
Score:
#348 in Microbiology
,
#2838 in Biology
,
#3552 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for Cilastatin
- Fisher Scientific - Search for Cilastatin
- TCI - Search for Cilastatin
- Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group. (Antimicrobial Agents and Chemotherapy, 1994)
- Thienamycin: development of imipenem-cilastatin (Journal of Antimicrobial Chemotherapy, 1983)
- Carbapenems, a new class of beta-lactam antibiotics: Discovery and development of imipenem/cilastatin (The American Journal of Medicine, 1985)
- Results of a multicenter trial comparing imipenem/cilastatin to tobramycin/clindamycin for intra-abdominal infections. (Annals of Surgery, 1990)
- Results of a Randomized Trial Comparing Sequential Intravenous/ Oral Treatment with Ciprofloxacin Plus Metronidazole to Imipenem/ Cilastatin for Intra-Abdominal Infections (Annals of Surgery, 1996)
- Comparison of tigecycline with imipenem/cilastatin for the treatment of hospital-acquired pneumonia. (Diagnostic Microbiology and Infectious Disease, 2010)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cilastatin Sodium
- MK-791
- MK 0791
- Cilastatin Monosodium Salt
- MK 791
- MK791
- MK0791
-
SMILESCC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)O)C
-
InChIKeyDHSUYTOATWAVLW-UHFFFAOYSA-N
- Pubchem - Cilastatin
- Wikipedia - cilastatin
Cilastatin is a chemical compound which inhibits the human enzyme dehydropeptidase. Dehydropeptidase is an enzyme found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin can therefore be combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Synthesis
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
Similar Compounds
gamma-Glu-gln
(1466-50-8)
8 alternate names
3 suppliers
gamma-Glutamylglutamate
(1116-22-9)
8 alternate names
3 suppliers
Imazapyr
(81334-34-1)
8 alternate names
1 safety hazard
3 suppliers
l-Alanyl-l-glutamine
(39537-23-0)
8 alternate names
3 suppliers
Nicotine bitartrate
(65-31-6)
8 alternate names
3 suppliers
DIISOBUTYL PHTHALATE
(84-69-5)
8 alternate names
3 safety hazards
3 suppliers
cycloheximide
(66-81-9)
8 alternate names
4 safety hazards
3 suppliers
ISOPROTHIOLANE
(50512-35-1)
8 alternate names
1 safety hazard
3 suppliers
Statobex
(50-58-8)
8 alternate names
3 suppliers
BENOMYL
(17804-35-2)
8 alternate names
7 safety hazards
3 suppliers
Thiophanate-methyl
(23564-05-8)
8 alternate names
5 safety hazards
3 suppliers
DIBUTYL SEBACATE
(109-43-3)
8 alternate names
3 suppliers
109-16-0
(109-16-0)
8 alternate names
3 suppliers
Alphozone
(123-23-9)
8 alternate names
3 suppliers
Thiophanate
(23564-06-9)
8 alternate names
3 suppliers
Plasticizer 3GH
(95-08-9)
8 alternate names
3 suppliers
Phenylacetylglutamine
(28047-15-6)
8 alternate names
3 suppliers
Clevudine
(163252-36-6)
8 alternate names
3 suppliers
5-Methyluridine
(1463-10-1)
8 alternate names
3 suppliers
Monochlorotyrosine
(7423-93-0, 7298-90-0)
8 alternate names
3 suppliers
21293-29-8
(21293-29-8)
8 alternate names
3 suppliers
dibutyl phthalate
(84-74-2)
8 alternate names
3 safety hazards
3 suppliers
DIHEXYL PHTHALATE
(68515-50-4, 68610-82-2, 84-75-3)
8 alternate names
1 safety hazard
3 suppliers
DIALLYL PHTHALATE
(131-17-9)
8 alternate names
4 safety hazards
3 suppliers
METALAXYL
(57837-19-1)
8 alternate names
2 safety hazards
3 suppliers
Dipentyl phthalate
(131-18-0)
8 alternate names
1 safety hazard
3 suppliers
Phenmedipham
(13684-63-4)
8 alternate names
3 safety hazards
3 suppliers
BIS(2-METHOXYETHYL) PHTHALATE
(117-82-8)
8 alternate names
1 safety hazard
3 suppliers
NOOTKATONE
(4674-50-4, 28834-25-5)
8 alternate names
3 suppliers
4674-50-4
(91416-23-8, 4674-50-4)
8 alternate names
3 suppliers
UNII-ZMS1VJK5HY
(38427-78-0, 4674-50-4)
8 alternate names
3 suppliers
DEHYDROACETIC ACID
(16807-48-0, 520-45-6)
8 alternate names
1 safety hazard
3 suppliers
BIS(2-BUTOXYETHYL) PHTHALATE
(117-83-9)
8 alternate names
3 suppliers
Methyl ricinoleate
(141-24-2)
8 alternate names
3 suppliers
methyl 12-hydroxyoctadec-9-enoate
(141-24-2)
8 alternate names
3 suppliers
Disperse yellow 3
(2832-40-8)
8 alternate names
1 safety hazard
3 suppliers
Disperse yellow 3
(2832-40-8)
8 alternate names
1 safety hazard
3 suppliers
Amiton oxalate
(3734-97-2)
8 alternate names
3 suppliers
Disperse yellow 3
(2832-40-8)
8 alternate names
1 safety hazard
3 suppliers
Diethanolamine oleate
(13961-86-9, 68855-44-7, 68439-43-0, 68130-87-0)
8 alternate names
3 suppliers
Dibutyl nonanedioate
(2917-73-9)
8 alternate names
3 suppliers
ARGININOSUCCINIC ACID
(2387-71-5)
8 alternate names
3 suppliers
S-nitrosoglutathione
(57564-91-7)
8 alternate names
3 suppliers
ANSERINE
(584-85-0)
8 alternate names
3 suppliers
Glyceryl monostearate
(83138-62-9, 11099-07-3, 31566-31-1, 37349-34-1, 123-94-4, 22610-63-5, 14811-92-8, 85666-92-8)
8 alternate names
3 suppliers
Tris(2-carboxyethyl)phosphine
(5961-85-3, 115-96-8)
8 alternate names
3 suppliers
3-HYDROXYCARBOFURAN
(16655-82-6)
8 alternate names
3 suppliers
Acetyl triethyl citrate
(77-89-4)
8 alternate names
3 suppliers
Phenylethylmalonamide
(7206-76-0)
8 alternate names
3 suppliers
carbofuran
(1563-66-2)
8 alternate names
5 safety hazards
3 suppliers
Benzyl butyl phthalate
(85-68-7)
8 alternate names
4 safety hazards
3 suppliers
Picloram
(50655-56-6, 1918-02-1)
8 alternate names
2 safety hazards
3 suppliers
CAS Directory
