| Weight | 199.162 g/mol |
|---|---|
| Formula | C8H9NO5 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
CLAVULANIC ACID (58001-44-8)
Clavulanate · Clavulanate Potassium · Potassium Clavulanate
Score:
#413 in Microbiology
,
#3275 in Biology
,
#4089 in Chemistry
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- Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus (Antimicrobial Agents and Chemotherapy, 1977)
- Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis (Science, 2009)
- Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase-positive strains resistant to amoxicillin-clavulanate: results of a national multicenter surveillance study. (Antimicrobial Agents and Chemotherapy, 1997)
- Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury is Influenced by Multiple HLA Class I and II Alleles (Gastroenterology, 2011)
- Treating Foot Infections in Diabetic Patients: A Randomized, Multicenter, Open-Label Trial of Linezolid versus Ampicillin-Sulbactam/Amoxicillin-Clavulanate (Clinical Infectious Diseases, 2004)
- In Vivo Activities of Amoxicillin and Amoxicillin-Clavulanate against Streptococcus pneumoniae: Application to Breakpoint Determinations (Antimicrobial Agents and Chemotherapy, 1998)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Clavulanate
- Clavulanate Potassium
- Potassium Clavulanate
- BRL14151
- BRL 14151
- MM 14151
- Clavulanic Acid, Monopotassium Salt
- MM-14151
- MM14151
- BRL-14151
- Sodium Clavulanate
- Clavulanic Acid, Monosodium Salt
-
SMILESC1C2N(C1=O)C(C(=CCO)O2)C(=O)O
-
InChIKeyHZZVJAQRINQKSD-UHFFFAOYSA-N
- Pubchem - CLAVULANIC ACID
- Wikipedia - clavulanic acid
Clavulanic acid () is a -lactam drug that functions as a mechanism-based -lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete -lactamase, which otherwise inactivates most penicillins. In its most common form, the potassium salt potassium clavulanate is combined with: amoxicillin (co-amoxiclav, trade names Augmentin, Tyclav, Synulox (veterinary), and others) ticarcillin (co-ticarclav, trade name Timentin) Clavulanic acid is an example of a clavam.
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