| Weight | 297.354 g/mol |
|---|---|
| Formula | C18H19NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
Codeinone (467-13-0)
6-codeinone · 6-codeinone, 2-t-labeled, (5alpha)-isomer
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- Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum (Plant Journal, 1999)
- Increasing morphinan alkaloid production by over-expressing codeinone reductase in transgenic Papaver somniferum. (Plant Biotechnology Journal, 2007)
- BIOTRANSFORMATION OF CODEINONE TO CODEINE BY IMMOBILIZED CELLS OF PAPAVER SOMNIFERUM (Phytochemistry, 1984)
- PURIFICATION AND PROPERTIES OF CODEINONE REDUCTASE (NADPH) FROM PAPAVER SOMNIFERUM CELL CULTURES AND DIFFERENTIATED PLANTS (FEBS Journal, 1995)
- Biotransformation of ()-codeinone to ()-codeine byPapaver somniferum cells immobilized in reticulate polyurethane foam (Plant Cell Reports, 1989)
- The synthesis of thebaine and northebaine from codeinone dimethyl ketal. (Journal of the American Chemical Society, 1967)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 6-codeinone
- 6-codeinone, 2-t-labeled, (5alpha)-isomer
-
SMILESCN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)C=C4
-
InChIKeyXYYVYLMBEZUESM-UHFFFAOYSA-N
- Pubchem - Codeinone
- Wikipedia - codeinone
Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone. The latter can also be synthesized from thebaine, however.
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