Weight | 321.446 g/mol |
---|---|
Formula | C16H23N3O2S |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 5 |
CP 122288 (143321-74-8)
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- Pubchem - CP 122288
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CP-122,288 is a drug which acts as a potent and selective agonist for the 5-HT1B, 5-HT1D and 5-HT1F serotonin receptor subtypes. It is a derivative of the migraine medication sumatriptan, but while CP-122,288 is 40,000 times more potent than sumatriptan as an inhibitor of neurogenic inflammation and plasma protein extravasation, it is only twice as potent as a constrictor of blood vessels. In human trials, CP-122,288 was not found to be effective as a treatment for migraine, but its selectivity for neurogenic anti-inflammatory action over vasoconstriction has made it useful for research into the underlying causes of migraine.
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