| Weight | 291.391 g/mol |
|---|---|
| Formula | C17H25NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
cyclopentolate (512-15-2)
Cyclogyl
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- Comparison of cyclopentolate versus tropicamide cycloplegia in children. (Optometry and Vision Science, 1993)
- Comparison of the effect of atropine and cyclopentolate on myopia (Annals of Ophthalmology, 1989)
- Pharmacokinetics of topically applied cyclopentolate HCl and tropicamide (Optometry and Vision Science, 1986)
- Systemic cyclopentolate (Cyclogyl) toxicity in the newborn infant. (The Journal of Pediatrics, 1973)
- The influence of drop size of cyclopentolate, phenylephrine and tropicamide on pupil dilatation and systemic side effects in infants (Acta Ophthalmologica Scandinavica, 2009)
- Cycloplegic Refraction in Esotropic Children: Cyclopentolate versus Atropine (Ophthalmology, 1981)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cyclogyl
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SMILESCN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O
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InChIKeySKYSRIRYMSLOIN-UHFFFAOYSA-N
- Pubchem - cyclopentolate
- Wikipedia - cyclopentolate
Cyclopentolate is a medication commonly used during pediatric eye examinations that dilates the eye (mydriatic), prevents accommodation of the eye to different distances (cycloplegic), and blocks specific receptors called muscarinic receptors (muscarinic antagonist). Cyclopentolate is also administered as an atropine substitute to reverse muscarinic and central nervous system effects of indirect cholinomimetic (anti-AChase) administration. When used in eye drops in paediatric eye examinations, cyclopentolate 0.5 percent and 1.0 percent is used to stop the eye focusing at any distance closer than infinity.
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Synthesis
Reactant
+
CYCLOPENTANONE
(Reformatsky reaction)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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cyclopentolate
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