| Weight | 314.257 g/mol |
|---|---|
| Formula | C14H10N4O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
dantrolene (7261-97-4)
Dantrolene Sodium · Dantrium
Score:
#80 in Neurology
,
#403 in Neuroscience
,
#1842 in Biology
,
#2206 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for dantrolene
- Fisher Scientific - Search for dantrolene
- TCI - Search for dantrolene
- Dantrolene A review of its pharmacology, therapeutic use and new developments (Anaesthesia, 2004)
- Studies on the mechanism of action of dantrolene sodium. A skeletal muscle relaxant. (Naunyn-schmiedebergs Archives of Pharmacology, 1972)
- Dantrolene Prevents Glutamate Cytotoxicity and Ca2+ Release from Intracellular Stores in Cultured Cerebral Cortical Neurons (Journal of Neurochemistry, 1991)
- Calcium release from skeletal muscle sarcoplasmic reticulum: site of action of dantrolene sodium (Science, 1976)
- In vitro antioxidant properties of dantrolene sodium. (Pharmacological Research, 2001)
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia (Embo Molecular Medicine, 2012)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Dantrolene Sodium
- Dantrium
-
SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
-
InChIKeyOZOMQRBLCMDCEG-UHFFFAOYSA-N
- Pubchem - dantrolene
- Wikipedia - dantrolene
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. It is the primary drug used for the treatment and prevention of malignant hyperthermia, a rare, life-threatening disorder triggered by general anesthesia.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Synthesis
Reactant
+
4-Chloronitrobenzene
(Suzuki)
Reactant
+
4-Chloronitrobenzene
(Decarboxylative coupling)
Similar Compounds
DANTROLENE SODIUM
(14663-23-1, 24868-20-0)
3 alternate names
3 suppliers
DANTROLENE SODIUM
(14663-23-1)
3 alternate names
3 suppliers
DANTROLENE SODIUM
(24868-20-0, 14663-23-1)
3 alternate names
3 suppliers
Colep
(2665-30-7)
3 alternate names
3 suppliers
EPN
(2104-64-5)
3 alternate names
3 safety hazards
3 suppliers
Dalamar Yellow
(6358-31-2)
3 alternate names
3 suppliers
6-NITROCHRYSENE
(7496-02-8)
3 alternate names
1 safety hazard
3 suppliers
2-Nitrofluorene
(607-57-8)
3 alternate names
2 safety hazards
3 suppliers
Pyrinuron
(53558-25-1)
3 alternate names
1 safety hazard
3 suppliers
Naphazoline nitrate
(10061-11-7, 5144-52-5)
3 alternate names
3 suppliers
2425-85-6
(2425-85-6)
3 alternate names
3 suppliers
PARAOXON
(311-45-5)
3 alternate names
3 suppliers
N,N'-Diacetylbenzidine
(613-35-4)
3 alternate names
4 safety hazards
3 suppliers
BULAN
(117-26-0, 25154-54-5)
3 alternate names
3 suppliers
parathion
(56-38-2)
3 alternate names
6 safety hazards
3 suppliers
2-METHYL-1-NITROANTHRAQUINONE
(129-15-7)
3 alternate names
1 safety hazard
3 suppliers
UNII-OE8ZA0KN9Z
(2814-77-9)
3 alternate names
3 suppliers
Pigment red 4
(2814-77-9)
3 alternate names
3 suppliers
2814-77-9
(2814-77-9)
3 alternate names
3 suppliers
4-NITRODIPHENYLAMINE
(836-30-6)
3 alternate names
2 safety hazards
3 suppliers
Parathion-methyl
(298-00-0)
3 alternate names
9 safety hazards
3 suppliers
Thiophanate-methyl
(23564-05-8)
3 alternate names
5 safety hazards
3 suppliers
1-NITROPYRENE
(63021-86-3, 5522-43-0)
3 alternate names
2 safety hazards
3 suppliers
Mesotrione
(104206-82-8)
3 alternate names
2 safety hazards
3 suppliers
4-NITROPYRENE
(57835-92-4)
3 alternate names
1 safety hazard
3 suppliers
5-NITROACENAPHTHENE
(602-87-9)
3 alternate names
2 safety hazards
3 suppliers
Niridazole
(61-57-4)
3 alternate names
3 suppliers
3-Pyridinecarboxylicacid, 2-[1-[2-[[(3,5-difluorophenyl)amino]carbonyl]hydrazinylidene]ethyl]-
(109293-97-2)
3 alternate names
3 suppliers
BIFENOX
(42576-02-3)
3 alternate names
3 suppliers
3-Nitrobenzo(a)pyrene
(70021-98-6)
3 alternate names
3 suppliers
2-Nitrobiphenyl
(28984-85-2, 86-00-0)
3 alternate names
3 suppliers
N-Hydroxy-2-acetamidofluorene
(53-95-2)
3 alternate names
3 suppliers
DINOTERB
(1420-07-1)
3 alternate names
3 safety hazards
3 suppliers
NAPTALAM
(132-66-1)
3 alternate names
3 suppliers
2-NITRONAPHTHALENE
(581-89-5)
3 alternate names
3 safety hazards
3 suppliers
Thiophanate
(23564-06-9)
3 alternate names
3 suppliers
3'-Nitroacetophenone
(121-89-1)
3 alternate names
3 suppliers
4'-Nitroacetophenone
(100-19-6)
3 alternate names
3 suppliers
2-Nitrodiphenylamine
(119-75-5)
3 alternate names
3 suppliers
9-NITROANTHRACENE
(602-60-8)
3 alternate names
3 suppliers
N,N-Diethyl-4-nitroaniline
(2216-15-1)
3 alternate names
3 suppliers
PENTACHLORONITROBENZENE
(100-00-5, 82-68-8)
3 alternate names
5 safety hazards
3 suppliers
2-Acetamidofluorene
(53-96-3)
3 alternate names
3 suppliers
DINOSEB
(88-85-7)
3 alternate names
8 safety hazards
3 suppliers
1-NITRONAPHTHALENE
(86-57-7, 27254-36-0)
3 alternate names
3 suppliers
CARBADOX
(6804-07-5)
3 alternate names
4 safety hazards
3 suppliers
78587-05-0
(78587-05-0)
3 alternate names
3 safety hazards
3 suppliers
(4s)-5-(4-chlorophenyl)-n-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide
(78587-05-0)
3 alternate names
3 safety hazards
3 suppliers
Naphthisen
(10061-11-7)
3 alternate names
3 suppliers
COUMAFURYL
(117-52-2)
3 alternate names
2 safety hazards
3 suppliers
Phentolamine mesylate
(65-28-1)
3 alternate names
3 suppliers
Bretylium tosylate
(61-75-6)
3 alternate names
3 suppliers
BENZNIDAZOLE
(22994-85-0)
3 alternate names
3 suppliers
Fuchsine Base
(3248-93-9)
3 alternate names
3 suppliers
PROMETHAZINE HYDROCHLORIDE
(58-33-3)
3 alternate names
3 suppliers
Algaphan
(1639-60-7)
3 alternate names
3 suppliers
BENOMYL
(17804-35-2)
3 alternate names
7 safety hazards
3 suppliers
CAS Directory
