| Weight | 232.239 g/mol |
|---|---|
| Formula | C12H12N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
DAZOXIBEN (103735-00-8, 78218-09-4)
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- Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries. (Circulation, 1984)
- SELECTIVE INHIBITION OF THROMBOXANE SYNTHETASE BY DAZOXIBEN INCREASES PROSTACYCLIN PRODUCTION BY LEUCOCYTES IN ANGINA PATIENTS AND HEALTHY VOLUNTEERS (The Lancet, 1982)
- Administration of dazoxiben, a selective thromboxane synthetase inhibitor, in the adult respiratory distress syndrome. (Chest, 1985)
- Controlled double-blind trial of dazoxiben and nifedipine in the treatment of Raynaud's phenomenon (The American Journal of Medicine, 1984)
- Dazoxiben in human sepsis and adult respiratory distress syndrome (Clinical Pharmacology & Therapeutics, 1985)
- Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism. (Journal of Pharmacology and Experimental Therapeutics, 1984)
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SMILESC1=CC(=CC=C1C(=O)O)OCCN2C=CN=C2
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- Pubchem - DAZOXIBEN
- Wikipedia - dazoxiben
Dazoxiben is an orally active thromboxane synthase inhibitor. It has shown a significant clinical improvement in patients with Raynaud's syndrome.
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