Weight | 478.633 g/mol |
---|---|
Formula | C29H38N2O4 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
Dehydroemetine
dehydroemetine hydrochloride
4914-30-1, 1986-67-0, 26266-12-6
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- Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis (Journal of Microencapsulation, 1989)
- Coated dosage form adapted to oral emetine or dehydroemetine therapy (1968)
- Comparative Pharmacokinetic Studies of Dehydroemetine and Emetine in Guinea Pigs Using Spectrofluorometric and Radiometric Methods (American Journal of Tropical Medicine and Hygiene, 1965)
- A comparative trial of dehydroemetine and emetine hydrochloride in identical dosage in amoebic liver abscess (Annals of Tropical Medicine and Parasitology, 1967)
- Dehydroemetine in amebic dysentery and amebic liver abscess. (American Journal of Tropical Medicine and Hygiene, 1962)
- An enzymatic electrocardiographic study on toxicity of dehydroemetine. (Heart, 1966)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - dehydroemetine hydrochloride
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SMILESCCC1=C(CC2C3=CC(=C(C=C3CCN2C1)OC)OC)CC4C5=CC(=C(C=C5CCN4)OC)OC
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InChIKeyXXLZPUYGHQWHRN-UHFFFAOYSA-N
- Pubchem - Dehydroemetine
- Wikipedia - Dehydroemetine
Dehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure (they differ only in a double bond next to the ethyl substituent), but it produces fewer side effects. In the United States, it is manufactured by Roche.
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