| Weight | 231.261 g/mol |
|---|---|
| Formula | C12H16F3N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
Dexfenfluramine (3239-44-9)
Score:
#342 in Neuroscience
,
#1546 in Biology
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- International trial of long-term dexfenfluramine in obesity (The Lancet, 1989)
- An Assessment of Heart-Valve Abnormalities in Obese Patients Taking Dexfenfluramine, Sustained-Release Dexfenfluramine, or Placebo (The New England Journal of Medicine, 1998)
- Anorexic Agents Aminorex, Fenfluramine, and Dexfenfluramine Inhibit Potassium Current in Rat Pulmonary Vascular Smooth Muscle and Cause Pulmonary Vasoconstriction (Circulation, 1996)
- Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension (Thorax, 2004)
- Valvular Abnormalities and Cardiovascular Status Following Exposure to Dexfenfluramine or Phentermine/Fenfluramine (JAMA, 2000)
- Effects of the cannabinoid receptor antagonist SR 141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats. (Psychopharmacology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCNC(C)CC1=CC(=CC=C1)C(F)(F)F
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InChIKeyDBGIVFWFUFKIQN-UHFFFAOYSA-N
- Pubchem - Dexfenfluramine
- Wikipedia - dexfenfluramine
Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain. It is the d-enantiomer of fenfluramine and is structurally similar to amphetamine, but lacks any psychologically stimulating effects. Dexfenfluramine was, for some years in the mid-1990s, approved by the United States Food and Drug Administration for the purposes of weight loss.
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