| Weight | 268.273 g/mol |
|---|---|
| Formula | C11H16N4O4 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
Dexrazoxane (24584-09-6)
Score:
#617 in Biochemistry
,
#1781 in Biology
,
#2121 in Chemistry
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- The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia (The New England Journal of Medicine, 2004)
- Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer. (Journal of Clinical Oncology, 1997)
- Topoisomerase IIMediated DNA Double-Strand Breaks: Implications in Doxorubicin Cardiotoxicity and Prevention by Dexrazoxane (Cancer Research, 2007)
- Dexrazoxane-Associated Risk for Acute Myeloid Leukemia/Myelodysplastic Syndrome and Other Secondary Malignancies in Pediatric Hodgkin's Disease (Journal of Clinical Oncology, 2007)
- Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial (Lancet Oncology, 2010)
- Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy. (Journal of Clinical Oncology, 1997)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
-
InChIKeyBMKDZUISNHGIBY-UHFFFAOYSA-N
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