| Weight | 420.513 g/mol |
|---|---|
| Formula | C15H24N4O6S2 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 7 |
Doripenem (148016-81-3, 364622-82-2)
Score:
#272 in Microbiology
,
#914 in Biochemistry
,
#2414 in Biology
,
#3005 in Chemistry
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- Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study* (Critical Care Medicine, 2008)
- Doripenem versus Pseudomonas aeruginosa In Vitro: Activity against Characterized Isolates, Mutants, and Transconjugants and Resistance Selection Potential (Antimicrobial Agents and Chemotherapy, 2004)
- Doripenem (S-4661), a novel carbapenem: comparative activity against contemporary pathogens including bactericidal action and preliminary in vitro methods evaluations (Journal of Antimicrobial Chemotherapy, 2004)
- Antimicrobial activity of doripenem (S-4661): a global surveillance report (2003) (Clinical Microbiology and Infection, 2005)
- Comparative activity of doripenem and three other carbapenems tested against Gram-negative bacilli with various -lactamase resistance mechanisms (Diagnostic Microbiology and Infectious Disease, 2005)
- Use of Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Support Phase 2 and 3 Dosing Strategies for Doripenem (Antimicrobial Agents and Chemotherapy, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1C2C(C(=O)N2C(=C1SC3CC(NC3)CNS(=O)(=O)N)C(=O)O)C(C)O
-
InChIKeyAVAACINZEOAHHE-UHFFFAOYSA-N
- Pubchem - Doripenem
- Wikipedia - doripenem
Doripenem is an ultra-broad-spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It was launched by Shionogi Co.
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