| Weight | 451.483 g/mol |
|---|---|
| Formula | C23H25N5O5 |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
doxazosin (74191-85-8)
Cardura · Doxazosin Mesylate · Progandol Neo
Score:
#920 in Biochemistry
,
#2440 in Biology
,
#3036 in Chemistry
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- The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia (The New England Journal of Medicine, 2003)
- Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) (JAMA, 2000)
- Efficacy and tolerability of doxazosin and finasteride, alone or in combination, in treatment of symptomatic benign prostatic hyperplasia: the Prospective European Doxazosin and Combination Therapy (PREDICT) trial. (Urology, 2003)
- Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial (The Lancet, 2015)
- Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder (BJUI, 2004)
- Doxazosin for the treatment of benign prostatic hyperplasia in patients with mild to moderate essential hypertension: a double-blind, placebo-controlled, dose-response multicenter study. (The Journal of Urology, 1995)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cardura
- Doxazosin Mesylate
- Progandol Neo
- Alpharma Brand of Doxazosin Mesylate
- Novopharm Brand of Doxazosin Mesylate
- Aliud Brand of Doxazosin Mesylate
- Doxazosina Alter
- Ciclum Brand of Doxazosin Mesylate
- UK 33274
- Doxazosin Wolff
- doxazosin von ct
- Gen Doxazosin
- Apo-Doxazosin
- Doxazosin AZU
- DoxaUro
- 1 (4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl)piperazine
- ct-Arzneimittel Brand of Doxazosin Mesylate
- Stadapharm Brand of Doxazosin
- Pharmagenus Brand of Doxazosin Mesylate
- Novo Doxazosin
- Doxagamma
- ratio Doxazosin
- Wrwag Brand of Doxazosin Mesylate
- Doxazosina Ratiopharm
- AstraZeneca Brand of Doxazosin Mesylate
- betapharm Brand of Doxazosin Mesylate
- MTW-Doxazosin
- Doxazosin beta
- Alfamedin
- Doxazosin Monohydrochloride
- Apotex Brand of Doxazosin Mesylate
- Doxazosin Klast
- Gen-Doxazosin
- Carduran Neo
- Doxazosina Geminis
- Doxazosina Ur
- Doxatensa
- Doxa-Puren
- Jutalar
- findusFit Brand of Doxazosin Mesylate
- Doxazosin Apogepha
- Doxazosina Combino Pharm
- Novo-Doxazosin
- Doxazosin findusFit
- Uriduct
- Zoxan
- Merck dura Brand of Doxazosin Mesylate
- Alter Brand of Doxazosin Mesylate
- Doxacor
- Genpharm Brand of Doxazosin Mesylate
- Hexal Brand of Doxazosin Mesylate
- Cinfa Brand of Doxazosin Mesylate
- Apogepha Brand of Doxazosin Mesylate
- Doxazosin-ratiopharm
- Doxa Puren
- Doxazosin Stada
- Doxazosin Heumann
- Doxazomerck
- Wolff Brand of Doxazosin Mesylate
- ct Arzneimittel Brand of Doxazosin Mesylate
- Geminis Brand of Doxazosin Mesylate
- Kade Brand of Doxazosin Mesylate
- Ratiopharm Brand of Doxazosin Mesylate
- Cantabria Brand of Doxazosin Mesylate
- Doxazosina Cinfa
- Combino Brand of Doxazosin Mesylate
- Doxazosin AL
- Azupharma Brand of Doxazosin Mesylate
- Carduran
- Q-Pharm Brand of Doxazosin Mesylate
- MTW Doxazosin
- MTW Brand of Doxazosin Mesylate
- Apo Doxazosin
- Q Pharm Brand of Doxazosin Mesylate
- TAD Brand of Doxazosin Mesylate
- Normon Brand of Doxazosin Mesylate
- Doxazosina Pharmagenus
- Linden Brand of Doxazosin Mesylate
- Juta Brand of Doxazosin Mesylate
- Doxamax
- Doxazosin-Wolff
- Cardular
- UK-33274
- Solvay Brand of Doxazosin Mesylate
- Heumann Brand of Doxazosin Mesylate
- Doxazosin ratiopharm
- Doxazosina Normon
- Pfizer Brand of Doxazosin Mesylate
- esparma Brand of Doxazosin Mesylate
- Almirall Brand of Doxazosin Mesylate
- Diblocin
- UK33274
- ratio-Doxazosin
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SMILESCOC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
-
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- Pubchem - doxazosin
- Wikipedia - doxazosin
Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an 1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH). In March 2000, the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) study stopped its arm of the trial looking at alpha blockers, because doxazosin was less effective than a simple diuretic, and because patients on doxazosin had a 25% higher rate of cardiovascular disease and twice the rate of congestive heart failure as patients on diuretics. Pfizer, aware of the results before publication, launched a marketing campaign in early 2000, and sales were largely unaffected, despite the dangers highlighted by the study.
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