| Weight | 761.85 g/mol |
|---|---|
| Formula | C39H43N3O11S |
| Hydrogen Acceptors | 15 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
ecteinascidin 743 (114899-77-3)
ET-743 · NSC 684766 · trabectedin
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- Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study (Lancet Oncology, 2007)
- Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair (Nature Medicine, 2001)
- Phase II Study of Ecteinascidin-743 in Advanced Pretreated Soft Tissue Sarcoma Patients (Journal of Clinical Oncology, 2004)
- DNA Sequence- and Structure-Selective Alkylation of Guanine N2 in the DNA Minor Groove by Ecteinascidin 743, a Potent Antitumor Compound from the Caribbean Tunicate Ecteinascidia turbinata (Biochemistry, 1996)
- Phase II and Pharmacokinetic Study of Ecteinascidin 743 in Patients With Progressive Sarcomas of Soft Tissues Refractory to Chemotherapy (Journal of Clinical Oncology, 2004)
- Enantioselective Total Synthesis of Ecteinascidin 743 (Journal of the American Chemical Society, 1996)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ET-743
- NSC 684766
- trabectedin
- Yondelis
- ET 743
-
SMILESCC1=C(C(=C2C3C4C5C6=C(C(N4C(C(N3C)CC2=C1)O)COC(=O)C7(CS5)C8=CC(=C(C=C8CCN7)O)OC)C9=C(C(=C6OC(=O)C)C)OCO9)O)OC
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InChIKeyPKVRCIRHQMSYJX-UHFFFAOYSA-N
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