| Weight | 174.203 g/mol |
|---|---|
| Formula | C10H10N2O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
edaravone (89-25-8)
3-methyl-1-phenyl-2-pyrazolin-5-one · MCI-186 · norantipyrine
Score:
#664 in Neuroscience
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#2955 in Biology
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#3696 in Chemistry
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- Effect of a Novel Free Radical Scavenger, Edaravone (MCI-186), on Acute Brain Infarction (Cerebrovascular Diseases, 2003)
- Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions. (Journal of Pharmacology and Experimental Therapeutics, 1994)
- Edaravone Reduces Early Accumulation of Oxidative Products and Sequential Inflammatory Responses After Transient Focal Ischemia in Mice Brain (Stroke, 2005)
- Neuroprotective Effects of Edaravone: a Novel Free Radical Scavenger in Cerebrovascular Injury (Cns Drug Reviews, 2006)
- Effects of a Novel Free Radical Scavenger, MCI-186, on Ischemic Brain Damage in the Rat Distal Middle Cerebral Artery Occlusion Model (Journal of Pharmacology and Experimental Therapeutics, 1997)
- Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro (Prostaglandins Leukotrienes and Essential Fatty Acids, 1988)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 3-methyl-1-phenyl-2-pyrazolin-5-one
- MCI-186
- norantipyrine
- edarabone
- phenylmethylpyrazolone
- MCI 186
- norphenazone
- 1-phenyl-3-methyl-5-pyrazolone
-
SMILESCC1=NN(C(=O)C1)C2=CC=CC=C2
-
InChIKeyQELUYTUMUWHWMC-UHFFFAOYSA-N
- Pubchem - edaravone
- Wikipedia - edaravone
Edaravone, sold as under the brand names Radicava and Radicut, is an intravenous medication used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis (ALS). The label carries a warning about the potential for hypersensitivity reactions to edaravone, and adverse effects include bruising, gait disturbances, headache, skin inflammation, eczema, problems breathing, excess sugar in urine, and fungal skin infections. The mechanism by which edaravone might be effective is unknown.
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