Weight | 182.17 g/mol |
---|---|
Formula | C6H12F2N2O2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 5 |
EFLORNITHINE (70052-12-9)
Difluoromethylornithine · Vaniqa · Ornidyl
Score:
#521 in Biochemistry
,
#1616 in Biology
,
#1904 in Chemistry
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- Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial. (Cancer Prevention Research, 2008)
- Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial (The Lancet, 2009)
- Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent (Clinical Cancer Research, 1999)
- Chemoprevention of Colon Carcinogenesis by Concurrent Administration of Piroxicam, a Nonsteroidal Antiinflammatory Drug with d,l--Difluoromethylornithine, an Ornithine Decarboxylase Inhibitor, in Diet (Cancer Research, 1990)
- Chemoprevention of Colon Carcinogenesis by Dietary Administration of Piroxicam, -Difluoromethylornithine, 16-Fluoro-5-androsten-17-one, and Ellagic Acid Individually and in Combination (Cancer Research, 1991)
- Inhibition of Ornithine Decarboxylase with 2-Difluoromethylornithine: Reduced Incidence of Dimethylhydrazine-induced Colon Tumors in Mice (Cancer Research, 1983)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Difluoromethylornithine
- Vaniqa
- Ornidyl
- Eflornithine Hydrochloride
- MDL71,782 A
- alpha Difluoromethyl Ornithine
- alpha-Difluoromethylornithine
- RMI 71782
- DL alpha Difluoromethylornithine
- Eflornithine Monohydrochloride, Monohydrate
- Monohydrochloride, Monohydrate Eflornithine
- alpha-Difluoromethyl Ornithine
- MDL 71,782 A
- alpha Difluoromethylornithine
- DL-alpha-Difluoromethylornithine
- MDL-71,782 A
-
SMILESC(CC(C(F)F)(C(=O)O)N)CN
-
InChIKeyVLCYCQAOQCDTCN-UHFFFAOYSA-N
- Pubchem - EFLORNITHINE
- Wikipedia - eflornithine
Eflornithine, sold under the brand name Vaniqa among others, is a medication used to treat African trypanosomiasis (sleeping sickness) and excessive hair growth on the face in women. Specifically it is used for the 2nd stage of sleeping sickness caused by T. b.
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