| Weight | 246.313 g/mol |
|---|---|
| Formula | C17H14N2 |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 0 |
ellipticine (519-23-3)
5,11-dimethyl-6H-pyrido(4,3-b)carbazole · NSC 71795 · ellipticine hydrochloride
Score:
#1801 in Physics
,
#2167 in Biochemistry
,
#5600 in Chemistry
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- Polymerdrug compatibility: A guide to the development of delivery systems for the anticancer agent, ellipticine (Journal of Pharmaceutical Sciences, 2004)
- Intercalators. 1. Nature of stacking interactions between intercalators (ethidium, daunomycin, ellipticine, and 4',6-diaminide-2-phenylindole) and DNA base pairs. Ab initio quantum chemical, density functional theory, and empirical potential study. (Journal of the American Chemical Society, 2002)
- Protein-associated DNA breaks in cells treated with adriamycin or ellipticine. (Biochimica et Biophysica Acta, 1978)
- Synthesis of the tumour-inhibitory alkaloids, ellipticine, 9-methoxyellipticine, and related pyrido[4,3-b]carbazoles (Australian Journal of Chemistry, 1967)
- Multimodal action of antitumor agents on DNA: The ellipticine series (Archives of Biochemistry and Biophysics, 1987)
- A convenient synthesis of 3-acylindoles via Friedel-Crafts acylation of 1-(phenylsulfonyl)indole. A new route to pyridocarbazole-5,11-quinones and ellipticine (Journal of Organic Chemistry, 1985)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 5,11-dimethyl-6H-pyrido(4,3-b)carbazole
- NSC 71795
- ellipticine hydrochloride
- ellipticine tartrate
-
SMILESCC1=C2C(=C(C3=C1C=CN=C3)C)C4=CC=CC=C4N2
-
InChIKeyCTSPAMFJBXKSOY-UHFFFAOYSA-N
- Pubchem - ellipticine
- Wikipedia - ellipticine
Ellipticine is an alkaloid first extracted from trees of the species Ochrosia elliptica and Rauvolfia sandwicensis, which inhibits the enzyme topoisomerase II via intercalative binding to DNA.
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