Weight | 220.272 g/mol |
---|---|
Formula | C12H16N2O2 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
Eltoprazine (98224-03-4, 98206-09-8)
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- Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze : profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP (Behavioural Pharmacology, 1992)
- Postsynaptic 5-HT1 receptors and offensive aggression in rats: A combined behavioural and autoradiographic study with eltoprazine (Pharmacology, Biochemistry and Behavior, 1991)
- Selective Antiaggressive Effects of Alnespirone in Resident-Intruder Test Are Mediated via 5-Hydroxytryptamine1A Receptors: A Comparative Pharmacological Study with 8-Hydroxy-2-Dipropylaminotetralin, Ipsapirone, Buspirone, Eltoprazine, and WAY-100635 (Journal of Pharmacology and Experimental Therapeutics, 1999)
- Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia (Movement Disorders, 2013)
- The effects of dorsal raphe administration of eltoprazine, TFMPP and 8-OH-DPAT on resident intruder aggression in the rat (European Journal of Pharmacology, 1993)
- Behavioural pharmacology of the serenic, eltoprazine. (Drug metabolism and drug interactions, 1990)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CN(CCN1)C2=C3C(=CC=C2)OCCO3
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InChIKeyWVLHGCRWEHCIOT-UHFFFAOYSA-N
- Pubchem - Eltoprazine
- Wikipedia - eltoprazine
Eltoprazine (DU-28,853) is a drug of the phenylpiperazine class which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor. It is closely related to fluprazine and batoprazine, which are similarly acting drugs.
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