| Weight | 302.422 g/mol |
|---|---|
| Formula | C17H26N4O |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
emedastine (87233-61-2)
Emadine · emedastine difumarate · KB 2413
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- Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females (Journal of Psychopharmacology, 2002)
- Histamine-stimulated cytokine secretion from human conjunctival epithelial cells: inhibition by the histamine H1 antagonist emedastine. (International Archives of Allergy and Immunology, 1998)
- Emedastine: A Potent, High Affinity Histamine H1-Receptor-Selective Antagonist for Ocular Use: Receptor Binding and Second Messenger Studies (Journal of Ocular Pharmacology and Therapeutics, 1994)
- Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use. (Journal of Ocular Pharmacology and Therapeutics, 1994)
- Inhibitory effects of emedastine difumarate on histamine release. (Japanese Journal of Pharmacology, 1993)
- Efficacy of olopatadine HCI 0.1%, ketotifen fumarate 0.025%, epinastine HCI 0.05%, emedastine 0.05% and fluorometholone acetate 0.1% ophthalmic solutions for seasonal allergic conjunctivitis: a placebo-controlled environmental trial. (Acta Ophthalmologica, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Emadine
- emedastine difumarate
- KB 2413
- KB-2413
- 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate
- KG-2413
- KG 2413
-
SMILESCCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C
-
InChIKeyKBUZBQVCBVDWKX-UHFFFAOYSA-N
- Pubchem - emedastine
- Wikipedia - emedastine
Emedastine (trade name Emadine) is a second generation antihistamine used in eye drops to alleviate the symptoms of allergic conjunctivitis. It acts as a H1 receptor antagonist. It works by blocking the action of histamine that causes allergic symptoms.
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