| Weight | 259.393 g/mol |
|---|---|
| Formula | C17H25NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
eperisone (64840-90-0, 56839-43-1)
E-0646 · (4'-ethyl-2-methyl-3-piperidino)propiophenone · 4-EMPP
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- Eperisone, an antispastic agent, possesses vasodilating actions on the guinea-pig basilar artery. (Journal of Pharmacology and Experimental Therapeutics, 1985)
- Rapid and sensitive liquid chromatography-electrospray ionization-mass spectrometry method for the determination of eperisone in human plasma: Method and clinical applications (Journal of Chromatographic Science, 2004)
- Intestinal first-pass metabolism of eperisone in the rat. (Pharmaceutical Research, 2001)
- Effect of a centrally-acting muscle relaxant, eperisone hydrochloride, on muscle sympathetic nerve activity in humans. (Functional Neurology, 1992)
- Efficacy and safety of eperisone in patients with low back pain: a double blind randomized study. (European Review for Medical and Pharmacological Sciences, 2008)
- Effects of tizanidine, eperisone and afloqualone on feline dorsal horn neuronal responses to peripheral cutaneous noxious and innocuous stimuli (Neuropharmacology, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - E-0646
- (4'-ethyl-2-methyl-3-piperidino)propiophenone
- 4-EMPP
-
SMILESCCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2
-
InChIKeySQUNAWUMZGQQJD-UHFFFAOYSA-N
- Pubchem - eperisone
- Wikipedia - eperisone
Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug. Eperisone acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. The drug inhibits the vicious circle of myotonia by decreasing pain, ischaemia, and hypertonia in skeletal muscles, thus alleviating stiffness and spasticity, and facilitating muscle movement Eperisone also improves dizziness and tinnitus associated with cerebrovascular disorders or cervical spondylosis.
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